Background Recently, the use of nanotechnology has been expanding very rapidly in
diverse areas of research, such as consumer products, energy, materials, and medicine …

Autophagy is required for benign hepatic tumors to progress into malignant hepatocellular
carcinoma. However, the mechanism is unclear. Here, we report that mitophagy, the …

Abstract p53 expression and acetylation are crucial for the survival and death of neurons in
penumbra. At the same time, the outcome of ischemia for penumbra cells depends largely …

Oxidative stress and inflammatory responses have been identified as key elements of
neuronal cell apoptosis. In this study, we investigated the mechanisms by which …

Background: Abnormal expression of microRNAs (miRNAs) is closely related to glioma,
which is one of the most common malignant brain tumors. The current study is to identify the …

Promoting regenerative repair, including neurogenesis and angiogenesis, may provide a
new therapeutic strategy for treatment of stroke. P53, a well-documented transcription factor …

Aims There is still no effective way to save a surviving healthy mind when there is critical
organ failure in the body. The next frontier in CTA is allo‐head and body reconstruction …

Cellular response to arsenic is strongly dependent on p53 functional status. Primarily
arresting the cell cycle in G1 or G2/M phases, arsenic treatment also induces an increase in …

Objective: Although cerebral ischemia can activate endogenous reparative processes, such
as proliferation of endogenous neural stem cells (NSCs) in the subventricular zone (SVZ) …

Cerebral ischemia is a serious cerebrovascular disease with the characteristics of high
morbidity, disability, and mortality. Currently, stem cell therapy has been extensively applied …