BRAF inhibitors in thyroid cancer: clinical impact, mechanisms of resistance and future perspectives
The Kirsten rat sarcoma viral oncogene homolog (RAS)/v-raf-1 murine leukemia viral
oncogene homolog 1 (RAF)/mitogen-activated protein kinase 1 (MAPK) signaling cascade is …
oncogene homolog 1 (RAF)/mitogen-activated protein kinase 1 (MAPK) signaling cascade is …
Osteopontin expression in thyroid cancer: deciphering EMT-related molecular mechanisms
BPPB Viana, AVP Gomes, ERP Gimba, LB Ferreira - Biomedicines, 2021 - mdpi.com
Thyroid cancer is the most common tumor arising from the endocrine system and generally
presents good prognosis. However, its aggressive subtypes are related to therapeutic …
presents good prognosis. However, its aggressive subtypes are related to therapeutic …
Impact of BRAF V600E and TERT Promoter Mutations on Response to Therapy in Papillary Thyroid Cancer
T Trybek, A Walczyk, D Gąsior-Perczak, I Pałyga… - …, 2019 - academic.oup.com
In this study, we examined the relationship between coexisting BRAF V600E and TERT
promoter mutations in papillary thyroid cancer (PTC) and response to therapy. PTC cases …
promoter mutations in papillary thyroid cancer (PTC) and response to therapy. PTC cases …
The BRAFV600E mutation analysis and risk stratification in papillary thyroid carcinoma
RS Scheffel, AP Cristo, M Romitti… - … of endocrinology and …, 2020 - SciELO Brasil
Objective: Although the prognostic role of BRAFV600E mutation in papillary thyroid
carcinoma (PTC) is controversial, the American Thyroid Association (ATA) includes the …
carcinoma (PTC) is controversial, the American Thyroid Association (ATA) includes the …
Impact of BRAFV600E Mutation on Event-Free Survival in Patients with Papillary Thyroid Carcinoma: A Retrospective Study in a Romanian Population
A Nechifor-Boilă, A Zahan, C Bănescu, V Moldovan… - Cancers, 2023 - mdpi.com
Simple Summary Although papillary thyroid carcinoma (PTC) is generally a highly curable
disease, there is a small subgroup of PTC cases that behaves more aggressively, with high …
disease, there is a small subgroup of PTC cases that behaves more aggressively, with high …
New biomarkers: prospect for diagnosis and monitoring of thyroid disease
MT Macvanin, ZM Gluvic, BL Zaric, M Essack… - Frontiers in …, 2023 - frontiersin.org
After the metabolic syndrome and its components, thyroid disorders represent the most
common endocrine disorders, with increasing prevalence in the last two decades. Thyroid …
common endocrine disorders, with increasing prevalence in the last two decades. Thyroid …
The role of the size in thyroid cancer risk stratification
F Vianello, S Censi, S Watutantrige-Fernando… - Scientific Reports, 2021 - nature.com
Only a minority of cases of differentiated thyroid carcinoma (DTC) have a poor clinical
outcome. Clinical outcomes and molecular aspects were assessed in: 144 DTC≤ 40 mm …
outcome. Clinical outcomes and molecular aspects were assessed in: 144 DTC≤ 40 mm …
Evaluation of the expression levels of BRAFV600E mRNA in primary tumors of thyroid cancer using an ultrasensitive mutation assay
Abstract Background The BRAF V600E gene encodes for the mutant BRAF V600E protein,
which triggers downstream oncogenic signaling in thyroid cancer. Since most currently …
which triggers downstream oncogenic signaling in thyroid cancer. Since most currently …
Elevated BANCR expression levels have different effects on papillary thyroid carcinoma progression depending on the presence of the BRAFV600E mutation
S Stojanović, S Šelemetjev, I Đorić, J Rončević… - European Journal of …, 2020 - Elsevier
Introduction The role of BRAF-activated non-protein coding RNA (BANCR) in papillary
thyroid carcinoma (PTC) is controversial, its clinical significance is unclear and no study has …
thyroid carcinoma (PTC) is controversial, its clinical significance is unclear and no study has …
Programmed cell death 4 (PDCD4) as a novel prognostic marker for papillary thyroid carcinoma
F Galuppini, M Fassan, L Bertazza… - Cancer management …, 2019 - Taylor & Francis
Background The primary goal of papillary thyroid cancer (PTC) management was to stratify
patients at pre-and post-surgical level to identify the small proportion of cases with …
patients at pre-and post-surgical level to identify the small proportion of cases with …