Cell-based and stem-cell-based treatments for spinal cord injury: evidence from clinical trials
Spinal cord injury is a severely disabling neurological condition leading to impaired mobility,
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
Central neuropathic pain
Central neuropathic pain arises from a lesion or disease of the central somatosensory
nervous system such as brain injury, spinal cord injury, stroke, multiple sclerosis or related …
nervous system such as brain injury, spinal cord injury, stroke, multiple sclerosis or related …
Multifunctional integrated nanozymes facilitate spinal cord regeneration by remodeling the extrinsic neural environment
High levels of reactive oxygen species (ROS) and inflammation create a complicated
extrinsic neural environment that dominates the initial post‐injury period after spinal cord …
extrinsic neural environment that dominates the initial post‐injury period after spinal cord …
Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury
Spinal cord injury (SCI) elicits chronic pain in 65% of individuals. In addition, SCI afflicts an
increasing number of aged individuals, and those with SCI are predisposed to shorter …
increasing number of aged individuals, and those with SCI are predisposed to shorter …
Central neuropathic mechanisms in pain signaling pathways: current evidence and recommendations
O Viswanath, I Urits, J Burns, K Charipova, K Gress… - Advances in …, 2020 - Springer
Purpose This is a comprehensive review of the current literature on central neuropathic pain
mechanisms that is secondary to spinal cord injury. It reviews recent and seminal findings on …
mechanisms that is secondary to spinal cord injury. It reviews recent and seminal findings on …
Assessment of neuropathic pain after spinal cord injury using quantitative pain drawings
Study design Clinimetric cross-sectional cohort study in adults with paraplegic spinal cord
injury (SCI) and neuropathic pain (NP). Objective To assess the reliability of standardized …
injury (SCI) and neuropathic pain (NP). Objective To assess the reliability of standardized …
Deep brain stimulation for locomotion in incomplete human spinal cord injury (DBS-SCI): protocol of a prospective one-armed multi-centre study
LH Stieglitz, AS Hofer, M Bolliger, MF Oertel, L Filli… - BMJ open, 2021 - bmjopen.bmj.com
Introduction Spinal cord injury (SCI) is a devastating condition with immediate impact on the
individual's health and quality of life. Major functional recovery reaches a plateau 3–4 …
individual's health and quality of life. Major functional recovery reaches a plateau 3–4 …
Biomarkers for predicting central neuropathic pain occurrence and severity after spinal cord injury: results of a long-term longitudinal study
H Gruener, G Zeilig, E Gaidukov, O Rachamim-Katz… - Pain, 2020 - journals.lww.com
Central neuropathic pain (CNP) after spinal cord injury (SCI) is debilitating and immensely
impacts the individual. Central neuropathic pain is relatively resistant to treatment …
impacts the individual. Central neuropathic pain is relatively resistant to treatment …
Indicators of central sensitization in chronic neuropathic pain after spinal cord injury
Background Central sensitization is considered a key mechanism underlying neuropathic
pain (NP) after spinal cord injury (SCI). Methods Two novel proxies for central sensitization …
pain (NP) after spinal cord injury (SCI). Methods Two novel proxies for central sensitization …
Conditioned pain modulation decreases over time in patients with neuropathic pain following a spinal cord injury
M Gagné, I Côté, M Boulet… - … and neural repair, 2020 - journals.sagepub.com
Background Neuropathic pain is a major problem following spinal cord injury (SCI). Central
mechanisms involved in the modulation of nociceptive signals have been shown to be …
mechanisms involved in the modulation of nociceptive signals have been shown to be …