At its re-birth 30 years ago, the neurodevelopment hypothesis of schizophrenia focussed on
aberrant genes and early neural hazards, but then it grew to include ideas concerning …

We propose that schizophrenia involves a combination of decreased phasic dopamine
responses for relevant stimuli and increased spontaneous phasic dopamine release. Using …

Prospective epidemiological studies have consistently demonstrated that cannabis use is
associated with an increased subsequent risk of both psychotic symptoms and …

The experience of childhood trauma (CT) and stressful life events (SLEs) is associated with
subsequent development of a variety of mental health conditions, including psychotic illness …

Long-term adverse experiences following psychedelic use can persist for weeks, months, or
even years, and are relatively unexplored in psychedelic research. Our convergent mixed …

Use of amphetamine and methamphetamine is widespread in the general population and
common among patients with psychiatric disorders. Amphetamines may induce symptoms of …

The studies of psychedelics, especially psychedelic tryptamines like psilocybin, are rapidly
gaining interest in neuroscience research. Much of this interest stems from recent clinical …

Background: Considering the pivotal role of negative emotional experiences in the
development and persistence of mental disorders, interfering with the consolidation …

Depression and anxiety are psychiatric diagnoses commonly associated with low quality of
life and low percentage of responsiveness by patients treated with currently available drugs …

Psychosis spectrum disorder (PSD) affects 1% of the world population and results in a
lifetime of chronic disability, causing devastating personal and economic consequences …