[HTML][HTML] Differentiation of bone marrow mesenchymal stem cells in osteoblasts and adipocytes and its role in treatment of osteoporosis

C Wang, H Meng, X Wang, C Zhao… - … medical journal of …, 2016 - ncbi.nlm.nih.gov
Osteoporosis is a systemic metabolic bone disorder characterized by a decrease in bone
mass and degradation of the bone microstructure, leaving bones that are fragile and prone …

Playing with bone and fat

JM Gimble, S Zvonic, ZE Floyd… - Journal of cellular …, 2006 - Wiley Online Library
The relationship between bone and fat formation within the bone marrow microenvironment
is complex and remains an area of active investigation. Classical in vitro and in vivo studies …

Aging alters bone-fat reciprocity by shifting in vivo mesenchymal precursor cell fate towards an adipogenic lineage

L Singh, TA Brennan, E Russell, JH Kim, Q Chen… - Bone, 2016 - Elsevier
Bone marrow derived mesenchymal progenitor cells (MPCs) play an important role in bone
homeostasis. Age-related changes occur in bone resulting in a decrease in bone density …

Total flavonoids of Herba Epimedii improves osteogenesis and inhibits osteoclastogenesis of human mesenchymal stem cells

JF Zhang, G Li, CL Meng, Q Dong, CY Chan, ML He… - Phytomedicine, 2009 - Elsevier
INTRODUCTION: In China Herba Epimedii is one of the most common herbs that could be
prescribed for treating osteoporosis. It is known to increase the overall mineral content …

The effects of ageing on differentiation and characterisation of human mesenchymal stem cells

H Khan, P Mafi, R Mafi, W Khan - Current stem cell research & …, 2018 - ingentaconnect.com
Background: Mesenchymal stem cells (MSC) are unique in their ability to self-renew and
differentiate into one of many lineage possibilities. It is therefore integral to preserve these …

Stem-cell, precursor cell, or target cell-based treatment of multi-organ failure and renal dysfunction

C Westenfelder - US Patent 8,603,462, 2013 - Google Patents
Methods for the treatment of acute renal failure, multi-organ failure, early dysfunction of
kidney transplant, chronic renal failure, organ dysfunction, and wound healing are provided …

Mesenchymal stem cells: a revolution in therapeutic strategies of age-related diseases

Y Peng, S Huang, B Cheng, X Nie, J Enhe… - Ageing research …, 2013 - Elsevier
The great evolutionary biologist Theodosius Dobzhansky once said:“Nothing in biology
makes sense except in the light of evolution”. Aging is a complex biological phenomenon …

Bone regeneration with BMP-2 gene-modified mesenchymal stem cells seeded on nano-hydroxyapatite/collagen/poly (l-lactic Acid) scaffolds

JL Dong, LX Li, WD Mu, YH Wang… - Journal of bioactive …, 2010 - journals.sagepub.com
In this study, the capacity of bone morphogenetic protein 2 (BMP-2) gene-transfected bone
marrow-derived mesenchymal stem cells (MSCs) in combination with nano-hydroxyapatite …

Energy balance, myostatin, and GILZ: factors regulating adipocyte differentiation in belly and bone

X Shi, M Hamrick, CM Isales - PPAR research, 2007 - Wiley Online Library
Peroxisome proliferator‐activated receptor gamma (PPAR‐γ) belongs to the nuclear
hormone receptor subfamily of transcription factors. PPARs are expressed in key target …

Mesenchymal stem cell biology, application and its role in regenerative medicine

A Dehghani Fard, N Saki, M Ahmadvand… - Scientific Journal of …, 2012 - bloodjournal.ir
Materials and Methods In the present study more than 100 recent published articles which
are about isolation, culture and differentiation of MSCs were reviewed for application of MSC …