Metal–Organic Frameworks for Nerve Repair and Neural Stem Cell Therapy

L Meng, N Ren, M Dong, S Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Recently, neurological disorders have led to a growing global burden of fatalities and
disabilities. The limited capacity for natural self‐regeneration poses a significant challenge …

Exoskeleton-assisted rehabilitation and neuroplasticity in spinal cord injury

Y He, Y Xu, M Hai, Y Feng, P Liu, Z Chen, W Duan - World Neurosurgery, 2024 - Elsevier
Spinal cord injury (SCI) results in neurological deficits below the level of injury, causing
motor dysfunction and various severe multisystem complications. Rehabilitative training …

Exosomes derived from schwann cells alleviate mitochondrial dysfunction and necroptosis after spinal cord injury via AMPK signaling pathway-mediated mitophagy

B Xu, Z Zhou, J Fang, J Wang, K Tao, J Liu… - Free Radical Biology and …, 2023 - Elsevier
Although spinal cord injury (SCI) represents a primary etiology of disability, currently, there
are exist limited viable therapies modalities. Acquiring comprehension of the diverse …

Tetramethylpyrazine-loaded electroconductive hydrogels promote tissue repair after spinal cord injury by protecting the blood–spinal cord barrier and neurons

B Deng, S Jiang, G Liu, X Li, Y Zhao, X Fan… - Journal of Materials …, 2024 - pubs.rsc.org
Spinal cord injury (SCI) usually induces profound microvascular dysfunction. It disrupts the
integrity of the blood–spinal cord barrier (BSCB), which could trigger a cascade of …

[HTML][HTML] ADSC-Exos enhance functional recovery after spinal cord injury by inhibiting ferroptosis and promoting the survival and function of endothelial cells through …

S Wu, Z Chen, Y Wu, Q Shi, E Yang, B Zhang… - Biomedicine & …, 2024 - Elsevier
Background Spinal cord injury (SCI) is a devastating disease that causes major motor,
sensory and autonomic dysfunctions. Currently, there is a lack of effective treatment. In this …

Multifunctional Conductive and Electrogenic Hydrogel Repaired Spinal Cord Injury via Immunoregulation and Enhancement of Neuronal Differentiation

M Liu, W Zhang, S Han, D Zhang, X Zhou… - Advanced …, 2024 - Wiley Online Library
Spinal cord injury (SCI) is a refractory neurological disorder. Due to the complex
pathological processes, especially the secondary inflammatory cascade and the lack of …

Resolvin D2 activates anti-inflammatory microglia via restoring autophagy flux and alleviate neuropathic pain following spinal cord injury in rats

L Yang, X Gao, D Tian, W Yang, S Xue, Z Cao… - Experimental …, 2023 - Elsevier
Spinal cord injury (SCI) is a fatal and intractable disease accompanied by the comorbidity of
chronic neuropathic pain. Here, we purposed to explore the therapeutic effect and the …

Improved Recovery of Complete Spinal Cord Transection by a Plasma-Modified Fibrillar Scaffold

D Osorio-Londoño, Y Heras-Romero… - Polymers, 2024 - mdpi.com
Complete spinal cord injury causes an irreversible disruption in the central nervous system,
leading to motor, sensory, and autonomic function loss, and a secondary injury that …

Risk of fracture among patients with spinal cord injury: A nationwide cohort study in South Korea

S Kim, B Kim, KD Han, J Park, JE Yoo, HL Choi… - Bone, 2024 - Elsevier
Background Clinical concerns about preventing and managing fractures after spinal cord
injury (SCI) have been growing. Objective This study investigates the risk of fractures among …

In Situ Reaction-Generated Aldehyde-Scavenging Polypeptides-Curcumin Conjugate Nanoassemblies for Combined Treatment of Spinal Cord Injury

Y Liu, F Lin, C Wu, W Liu, H Wang, C Xiao, X Chen - ACS nano, 2024 - ACS Publications
The microenvironment after traumatic spinal cord injury (SCI) involves complex pathological
processes, including elevated oxidative stress, accumulated reactive aldehydes from lipid …