Spatiotemporal multi-omics: exploring molecular landscapes in aging and regenerative medicine
Aging and regeneration represent complex biological phenomena that have long captivated
the scientific community. To fully comprehend these processes, it is essential to investigate …
the scientific community. To fully comprehend these processes, it is essential to investigate …
Advancements in neuroregenerative and neuroprotective therapies for traumatic spinal cord injury
G Fischer, L Bättig, MN Stienen, A Curt… - Frontiers in …, 2024 - frontiersin.org
Traumatic spinal cord injuries (SCIs) continue to be a major healthcare concern, with a rising
prevalence worldwide. In response to this growing medical challenge, considerable …
prevalence worldwide. In response to this growing medical challenge, considerable …
Current multi-scale biomaterials for tissue regeneration following spinal cord injury
Y ang Zhang, Z huan Wu, J feng Wu, T dong Li… - Neurochemistry …, 2024 - Elsevier
Spinal cord injury (SCI) may cause loss of motor and sensory function, autonomic
dysfunction, and thus disrupt the quality of life of patients, leading to severe disability and …
dysfunction, and thus disrupt the quality of life of patients, leading to severe disability and …
Platelet-rich plasma-derived exosomes promote blood-spinal cord barrier repair and attenuate neuroinflammation after spinal cord injury
X Nie, Y Liu, T Yuan, T Yu, Z Yun, W Xue, T Yu… - Journal of …, 2024 - Springer
Spinal cord injury (SCI) compromises the blood-spinal cord barrier (BSCB) and induces
neuroinflammation, potentially exacerbating neuronal damage. This underscores the …
neuroinflammation, potentially exacerbating neuronal damage. This underscores the …
Hydrogel-based therapeutic strategies for spinal cord injury repair: Recent advances and future prospects
N Li, J He - International Journal of Biological Macromolecules, 2024 - Elsevier
Spinal cord injury (SCI) is a debilitating condition that can result in significant functional
impairment and loss of quality of life. There is a growing interest in developing new …
impairment and loss of quality of life. There is a growing interest in developing new …
MicroRNA-9 promotes axon regeneration of mauthner-cell in zebrafish via her6/ calcium activity pathway
Y Shen, X Chen, Z Song, H Yao, A Han… - Cellular and Molecular …, 2024 - Springer
MicroRNA (miRNA), functioning as a post-transcriptional regulatory element, plays a
significant role in numerous regulatory mechanisms and serves as a crucial intrinsic factor …
significant role in numerous regulatory mechanisms and serves as a crucial intrinsic factor …
[HTML][HTML] New strategy to treat spinal cord injury: Nafamostat mesilate suppressed NLRP3-mediated pyroptosis during acute phase
Y Lou, Z Li, H Zheng, Z Yuan, W Li, J Zhang… - International …, 2024 - Elsevier
Spinal cord injury (SCI) is a devastating condition for which effective clinical treatment is
currently lacking. During the acute phase of SCI, myriad pathological changes give rise to …
currently lacking. During the acute phase of SCI, myriad pathological changes give rise to …
[HTML][HTML] A biomimic anti-neuroinflammatory nanoplatform for active neutrophil extracellular traps targeting and spinal cord injury therapy
C Tang, Y Jin, M Wu, F Jia, X Lu, J Li, J Wu, S Zhu… - Materials Today Bio, 2024 - Elsevier
Traumatic spinal cord injury (SCI) always leads to severe neurological deficits and
permanent damage. Neuroinflammation is a vital process of SCI and have become a …
permanent damage. Neuroinflammation is a vital process of SCI and have become a …
Influential factors on stem cell therapy success in canine model of spinal cord Injury: A systematic review and meta-analysis
A Dadvand, A Yavari, A Teimourpour… - Brain Research, 2024 - Elsevier
Spinal cord injury (SCI) is a serious medical condition. The search for an effective cure
remains a persistent challenge. Current treatments, unfortunately, are unable to sufficiently …
remains a persistent challenge. Current treatments, unfortunately, are unable to sufficiently …
Neutrophil membrane-coated multifunctional biomimetic nanoparticles for spinal cord injuries
H Zhu, F Cai, Z Li, L Zhang, X Zhou, J Yao… - Journal of …, 2024 - Taylor & Francis
Spinal cord injury (SCI) is one of the most complex diseases. After SCI, severe secondary
injuries can cause intense inflammatory storms and oxidative stress responses, leading to …
injuries can cause intense inflammatory storms and oxidative stress responses, leading to …