Abstract Spinal Cord Injury (SCI) is a debilitating disease associated with a significant
economic burden owing to its high level of disability; however, current treatment options …

Spinal cord injury (SCI) is a severe neurological complication following spinal fracture,
which has long posed a challenge for clinicians. Microglia play a dual role in the …

Spinal cord injury (SCI) induces the disruption of the blood–spinal cord barrier (BSCB) and
the failure of axonal growth. SCI activates a complex series of responses, including cell …

Changes in intracellular nicotinamide adenine dinucleotide (NAD+) levels have been
observed in various disease states. A decrease in NAD+ levels has been noted following …

Treating spinal cord injury usually involves promoting axonal regeneration, but glial scars
and other factors are insurmountable gaps. Activation of dormant relay pathways in the …

Urodelean amphibians can regenerate the tail and the spinal cord (SC) and maintain this
ability throughout their life. This clearly distinguishes these animals from mammals. The …

Neurons are the largest known cells, with processes ranging from millimeters to centimeters,
and axons that can reach meters in mammals (Terenzio et al., 2017). Their specialized …

The treatment of spinal cord injury (SCI) is often ineffective. Additionally, SCI-induced
inflammation leads to secondary injury. Current anti-inflammatory hydrophilic drugs fail to …

Spinal cord injury induces significant cellular stress responses. The Heat Shock Protein 90
(HSP90) plays a pivotal role as a molecular chaperone and is crucial for protein folding …

摘要背景: 前期研究证实, 温肾通督方可通过抑制脾脏B 细胞焦亡, 促进微血管内皮细胞吞噬髓鞘
碎片, 影响小胶质细胞迁移和浸润, 促进受损神经元恢复, 降低脊髓损伤后神经元凋亡等促进脊髓 …