Recent epidemiology studies highlighted the detrimental health effects of exposure to low
dose and low dose rate ionizing radiation (IR): nuclear industry workers studies have shown …

In the absence of physical data, biodosimetry tools are required for fast dose and risk
assessment in the event of radiological or nuclear mass accidents or attacks to triage …

This work presents an overview of the applications of retrospective dosimetry techniques in
case of incorporation of radionuclides. The fact that internal exposures are characterized by …

Biological monitoring of radiation exposure relies heavily on the quantification of
chromosome aberrations such as dicentrics and reciprocal translocations in the peripheral …

Telomeres consist of GC-rich DNA repeats and the “shelterin” protein complex that together
protect chromosome ends from fusion and degradation. Telomeres shorten with age due to …

The long-term in vivo cytogenetic effects of high-dose radiation exposure can be traced in
accidentally irradiated persons, and particularly useful for developing strategies of …

The method of fluorescence in situ hybridization (FISH) applied to peripheral blood T
lymphocytes is used for retrospective dose estimation, and the results obtained from the …

Cells exposed to ionizing radiation have a wide spectrum of DNA lesions that include DNA
single-strand breaks, DNA double-strand breaks (DSBs), oxidative base damage and DNA …

Abstract Evaluation of age effect on the frequency of radiation-induced translocations,
registered using FISH in circulating T-lymphocytes in the long-term period after exposure, is …

FISH analysis of chromosomal aberrations in T-lymphocytes from peripheral blood is used to
assess exposure doses. The interpretation of the results of cytogenetic studies requires …