Background Non-alcoholic fatty liver disease, or as recently proposed 'metabolic-associated
fatty liver disease'(MAFLD), is characterized by pathological accumulation of triglycerides …

BACKGROUND Life-forms ranging from bacteria to humans are programmed by circadian
clocks—mechanisms that impose an~ 24-hour rhythmicity on biology in harmony with …

Intervertebral disc degeneration (IDD) is a common clinical degenerative disease of the
spine. A series of factors, such as inflammation, oxidative stress and mechanical stress …

Adipose, skeletal, and hepatic muscle tissues are the main endocrine organs that produce
adipokines, myokines, and hepatokines. These biomarkers can be harmful or beneficial to …

Almost all living organisms have evolved autoregulatory transcriptional‐translational
feedback loops that produce oscillations with a period of approximately 24‐h. These …

Abstract In mammals, triglyceride (TG), the main form of lipids for storing and providing
energy, is stored in white adipose tissue (WAT) after food intake, while during fasting it is …

Inhibition of immunocyte infiltration and activation has been suggested to effectively
ameliorate nonalcoholic steatohepatitis (NASH). Paired immunoglobulin-like receptor B …

Food intake profoundly affects systemic physiology. A large body of evidence has indicated
a link between food intake and circadian rhythms, and~ 24‐h cycles are deemed essential …

Limited tumor permeability of therapeutic agents is a great challenge faced by current
cancer therapy methods. Herein, a kind of near infrared light (NIR)‐driven nanomotor with …

The circadian system is composed of coupled endogenous oscillators that allow living
beings, including humans, to anticipate and adapt to daily changes in their environment. In …