Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases

Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

[HTML][HTML] Non-coding RNA-mediated modulation of ferroptosis in cardiovascular diseases

Y Liu, W Ding, J Wang, X Ao, J Xue - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cardiovascular disease (CVD) is a major contributor to increasing morbidity and mortality
worldwide and seriously threatens human health and life. Cardiomyocyte death is …

[HTML][HTML] Ferritinophagy and ferroptosis in cardiovascular disease: Mechanisms and potential applications

Y Qin, Y Qiao, D Wang, C Tang, G Yan - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Ferroptosis is a type of regulated cell death driven by iron dependent accumulation of
cellular reactive oxygen species (ROS) when glutathione (GSH)-dependent lipid …

A portable sweat sensor based on carbon quantum dots for multiplex detection of cardiovascular health biomarkers

J Wei, X Zhang, SM Mugo, Q Zhang - Analytical Chemistry, 2022 - ACS Publications
The future of personalized diagnostics and treatment of cardiovascular diseases lies in the
use of portable sensors. Portable sensors can acquire biomarker information in biological …

Zooming in and out of ferroptosis in human disease

X Wang, Y Zhou, J Min, F Wang - Frontiers of Medicine, 2023 - Springer
Ferroptosis is defined as an iron-dependent regulated form of cell death driven by lipid
peroxidation. In the past decade, it has been implicated in the pathogenesis of various …

The link between ferroptosis and cardiovascular diseases: a novel target for treatment

H Hu, Y Chen, L Jing, C Zhai, L Shen - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Ferroptosis is an iron-dependent cell death, which is characterized by iron overload and
lipid peroxidation. Ferroptosis is distinct from apoptosis, necroptosis, autophagy, and other …

[HTML][HTML] CircP4HB regulates ferroptosis via SLC7A11-mediated glutathione synthesis in lung adenocarcinoma

CF Pan, K Wei, ZJ Ma, YZ He, JJ Huang… - … lung cancer research, 2022 - ncbi.nlm.nih.gov
Background Circular ribonucleic acids (circRNAs) play a key role in the development of
different types of cancer. Ferroptosis is a type of programmed cell death that contributes to …

ROS and iron homeostasis dependent ferroptosis play a vital role in 5-Fluorouracil induced cardiotoxicity in vitro and in vivo

D Li, C Song, J Zhang, X Zhao - Toxicology, 2022 - Elsevier
Fluorouracil (5-FU) was a key chemotherapeutic agent in the treatment of different solid
tumors. However, cardiotoxicity was included among the therapeutic strategies of 5-FU. The …

[HTML][HTML] PCSK9: A emerging participant in heart failure

Q Xu, Y Zhao, N He, R Gao, W Xu, X Zhuo… - Biomedicine & …, 2023 - Elsevier
Heart failure (HF) is a complex clinical syndrome caused by various cardiovascular
diseases. Its main pathogenesis includes cardiomyocyte loss, myocardial energy …

Targeting ferroptosis to treat cardiovascular diseases: a new continent to be explored

F Huang, R Yang, Z Xiao, Y Xie, X Lin, P Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular diseases, including cardiomyopathy, myocardial infarction, myocardial
ischemia/reperfusion injury, heart failure, vascular injury, stroke, and arrhythmia, are …