Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
[HTML][HTML] Non-coding RNA-mediated modulation of ferroptosis in cardiovascular diseases
Y Liu, W Ding, J Wang, X Ao, J Xue - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cardiovascular disease (CVD) is a major contributor to increasing morbidity and mortality
worldwide and seriously threatens human health and life. Cardiomyocyte death is …
worldwide and seriously threatens human health and life. Cardiomyocyte death is …
[HTML][HTML] Ferritinophagy and ferroptosis in cardiovascular disease: Mechanisms and potential applications
Y Qin, Y Qiao, D Wang, C Tang, G Yan - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Ferroptosis is a type of regulated cell death driven by iron dependent accumulation of
cellular reactive oxygen species (ROS) when glutathione (GSH)-dependent lipid …
cellular reactive oxygen species (ROS) when glutathione (GSH)-dependent lipid …
A portable sweat sensor based on carbon quantum dots for multiplex detection of cardiovascular health biomarkers
The future of personalized diagnostics and treatment of cardiovascular diseases lies in the
use of portable sensors. Portable sensors can acquire biomarker information in biological …
use of portable sensors. Portable sensors can acquire biomarker information in biological …
Zooming in and out of ferroptosis in human disease
X Wang, Y Zhou, J Min, F Wang - Frontiers of Medicine, 2023 - Springer
Ferroptosis is defined as an iron-dependent regulated form of cell death driven by lipid
peroxidation. In the past decade, it has been implicated in the pathogenesis of various …
peroxidation. In the past decade, it has been implicated in the pathogenesis of various …
The link between ferroptosis and cardiovascular diseases: a novel target for treatment
H Hu, Y Chen, L Jing, C Zhai, L Shen - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Ferroptosis is an iron-dependent cell death, which is characterized by iron overload and
lipid peroxidation. Ferroptosis is distinct from apoptosis, necroptosis, autophagy, and other …
lipid peroxidation. Ferroptosis is distinct from apoptosis, necroptosis, autophagy, and other …
[HTML][HTML] CircP4HB regulates ferroptosis via SLC7A11-mediated glutathione synthesis in lung adenocarcinoma
CF Pan, K Wei, ZJ Ma, YZ He, JJ Huang… - … lung cancer research, 2022 - ncbi.nlm.nih.gov
Background Circular ribonucleic acids (circRNAs) play a key role in the development of
different types of cancer. Ferroptosis is a type of programmed cell death that contributes to …
different types of cancer. Ferroptosis is a type of programmed cell death that contributes to …
ROS and iron homeostasis dependent ferroptosis play a vital role in 5-Fluorouracil induced cardiotoxicity in vitro and in vivo
D Li, C Song, J Zhang, X Zhao - Toxicology, 2022 - Elsevier
Fluorouracil (5-FU) was a key chemotherapeutic agent in the treatment of different solid
tumors. However, cardiotoxicity was included among the therapeutic strategies of 5-FU. The …
tumors. However, cardiotoxicity was included among the therapeutic strategies of 5-FU. The …
[HTML][HTML] PCSK9: A emerging participant in heart failure
Q Xu, Y Zhao, N He, R Gao, W Xu, X Zhuo… - Biomedicine & …, 2023 - Elsevier
Heart failure (HF) is a complex clinical syndrome caused by various cardiovascular
diseases. Its main pathogenesis includes cardiomyocyte loss, myocardial energy …
diseases. Its main pathogenesis includes cardiomyocyte loss, myocardial energy …
Targeting ferroptosis to treat cardiovascular diseases: a new continent to be explored
F Huang, R Yang, Z Xiao, Y Xie, X Lin, P Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular diseases, including cardiomyopathy, myocardial infarction, myocardial
ischemia/reperfusion injury, heart failure, vascular injury, stroke, and arrhythmia, are …
ischemia/reperfusion injury, heart failure, vascular injury, stroke, and arrhythmia, are …