Legionella Pneumophila Pathogenesis: A Fateful Journey from Amoebae to Macrophages

MS Swanson, BK Hammer - Annual Reviews in Microbiology, 2000 - annualreviews.org
▪ Abstract Legionella pneumophila first commanded attention in 1976, when investigators
from the Centers for Disease Control and Prevention identified it as the culprit in a massive …

Legionella pneumophila: an aquatic microbe goes astray

M Steinert, U Hentschel, J Hacker - FEMS microbiology reviews, 2002 - academic.oup.com
Legionella pneumophila is naturally found in fresh water were the bacteria parasitize within
protozoa. It also survives planctonically in water or biofilms. Upon aerosol formation via man …

The complete genome sequence of Francisella tularensis, the causative agent of tularemia

P Larsson, PCF Oyston, P Chain, MC Chu, M Duffield… - Nature …, 2005 - nature.com
Francisella tularensis is one of the most infectious human pathogens known. In the past,
both the former Soviet Union and the US had programs to develop weapons containing the …

Invasion of Protozoa by Legionella pneumophila and Its Role in Bacterial Ecology and Pathogenesis

Y Abu Kwaik, LY Gao, BJ Stone… - Applied and …, 1998 - Am Soc Microbiol
The first recognized outbreak of pneumonia due to Legionella pneumophila occurred in
Philadelphia, Pa., in July of 1976 among 180 persons attending the 56th annual American …

Dictyostelium discoideum: a new host model system for intracellular pathogens of the genus Legionella

S Hägele, R Köhler, H Merkert… - Cellular …, 2000 - Wiley Online Library
The soil amoeba Dictyostelium discoideum is a haploid eukaryote that, upon starvation,
aggregates and enters a developmental cycle to produce fruiting bodies. In this study, we …

Response of Chlamydia trachomatis serovar E to iron restriction in vitro and evidence for iron-regulated chlamydial proteins

JE Raulston - Infection and immunity, 1997 - Am Soc Microbiol
Iron is a well-established mediator of virulence in several bacterial pathogens, yet little is
known about the role of iron in infectious disease processes caused by obligate intracellular …

[HTML][HTML] Functional genomic studies of uropathogenic Escherichia coli and host urothelial cells when intracellular bacterial communities are assembled

CS Reigstad, SJ Hultgren, JI Gordon - Journal of Biological Chemistry, 2007 - ASBMB
Uropathogenic Escherichia coli (UPEC), the principal cause of urinary tract infection in
women, colonizes the gut as well as the genitourinary tract. Studies of mice inoculated with …

Pathogenicity of Legionella pneumophila

NP Cianciotto - International Journal of Medical Microbiology, 2001 - Elsevier
The bacterium Legionella pneumophila is the principal etiologic agent of Legionnaires'
disease, a form of lobar pneumonia. Ubiquitous in aquatic environments, the gram-negative …

Legionella pneumophila feoAB Promotes Ferrous Iron Uptake and Intracellular Infection

M Robey, NP Cianciotto - Infection and immunity, 2002 - Am Soc Microbiol
In order to determine the role of ferrous iron transport in Legionella pathogenesis, we
identified and mutated the feoB gene in virulent Legionella pneumophila strain 130b. As it is …

Confrontation between intracellular bacteria and the immune system

UE Schaible, HL Collins, SHE Kaufmann - Advances in immunology, 1998 - Elsevier
Publisher Summary The complex contest between bacteria and the mammalian host follows
different game plans that are undertaken to ensure the survival of both the pathogen and the …