Pine nut antioxidant peptides ameliorate the memory impairment in a scopolamine-induced mouse model via SIRT3-induced synaptic plasticity

H Lu, L Fang, J Wang, F Zhao, C Liu, Y Gao, J Liu… - Food & Function, 2021 - pubs.rsc.org
This study aimed to investigate the effects of a pine nut albumin hydrolysate (fraction< 3
kDa) and of its short peptide derivative, Trp-Tyr-Pro-Gly-Lys (WYPGK), on synaptic plasticity …

The role of microglial activation on ischemic stroke: modulation by fibroblast growth factors

C Dordoe, W Huang, C Bwalya, X Wang, B Shen… - Cytokine & Growth …, 2023 - Elsevier
Stroke is one of the devastating clinical conditions that causes death and permanent
disability. Its occurrence causes the reduction of oxygen and glucose supply, resulting in …

MicroRNA Let-7f-5p promotes bone marrow mesenchymal stem cells survival by targeting caspase-3 in Alzheimer disease model

L Han, Y Zhou, R Zhang, K Wu, Y Lu, Y Li… - Frontiers in …, 2018 - frontiersin.org
Widespread death of transplanted mesenchymal stem cells (MSCs) hampers the
development of stem cell therapy for Alzheimer disease (AD). Cell pre-conditioning might …

Prospects for the application of mesenchymal stem cells in Alzheimer's disease treatment

F Chakari-Khiavi, S Dolati, A Chakari-Khiavi… - Life sciences, 2019 - Elsevier
Alzheimer's disease (AD) as a dementia and neurodegenerative disease, is mostly
prevalent among people more than 65 years. AD is mostly manifested in the form of …

Umbilical cord-derived mesenchymal stem cells in neurodegenerative disorders: from literature to clinical practice

S Reyhani, B Abbaspanah, SH Mousavi - Regenerative medicine, 2020 - Taylor & Francis
Mesenchymal stem cells (MSCs) have provided a promising tool for cell therapy. Umbilical
cord (UC) is one of the best sources of MSCs since its collection is noninvasive, and …

Raspberry polyphenols alleviate neurodegenerative diseases: through gut microbiota and ROS signals

B Hu, Y Shi, C Lu, H Chen, Y Zeng, J Deng, L Zhang… - Food & Function, 2023 - pubs.rsc.org
Neurodegenerative diseases are neurological disorders that become more prevalent with
age, usually caused by damage or loss of neurons or their myelin sheaths, such as …

Extracellular vesicles from mesenchymal stem cells exert pleiotropic effects on amyloid‐β, inflammation, and regeneration: a spark of hope for Alzheimer's disease …

CA Elia, M Losurdo, ML Malosio, S Coco - Bioessays, 2019 - Wiley Online Library
No cure yet exists for devastating Alzheimer's disease (AD), despite many years and
humongous efforts to find efficacious pharmacological treatments. So far, neither designing …

Current advancement of immunomodulatory drugs as potential pharmacotherapies for autoimmunity based neurological diseases

H Ashraf, P Solla, LA Sechi - Pharmaceuticals, 2022 - mdpi.com
Dramatic advancement has been made in recent decades to understand the basis of
autoimmunity-mediated neurological diseases. These diseases create a strong influence on …

Stem cell‐based cell therapy for neuroprotection in stroke: A review

R Rikhtegar, M Yousefi, S Dolati… - Journal of cellular …, 2019 - Wiley Online Library
Neurological disorders, such as stroke, are triggered by a loss of neurons and glial cells.
Ischemic stroke remains a substantial problem for industrialized countries. Over the previous …

Representing Diversity in the Dish: Using Patient-Derived in Vitro Models to Recreate the Heterogeneity of Neurological Disease

LT Ghaffari, A Starr, AT Nelson, R Sattler - Frontiers in neuroscience, 2018 - frontiersin.org
Neurological diseases, including dementias such as Alzheimer's disease (AD) and fronto-
temporal dementia (FTD) and degenerative motor neuron diseases such as amyotrophic …