Colloidal gels: Equilibrium and non-equilibrium routes

E Zaccarelli - Journal of Physics: Condensed Matter, 2007 - iopscience.iop.org
We attempt a classification of different colloidal gels based on colloid–colloid interactions.
We discriminate primarily between non-equilibrium and equilibrium routes to gelation, the …

Sickle‐cell haemoglobin polymerization: is it the primary pathogenic event of sickle‐cell anaemia?

PG Vekilov - British journal of haematology, 2007 - Wiley Online Library
Sickle cell anaemia is associated with a mutant haemoglobin, HbS, which forms polymers in
the red blood cells of patients. The primary role of the HbS polymerization for the …

One-dimensional cluster growth and branching gels in colloidal systems with short-range depletion attraction and screened electrostatic repulsion

F Sciortino, P Tartaglia, E Zaccarelli - The Journal of Physical …, 2005 - ACS Publications
We report extensive numerical simulations of a simple model for charged colloidal particles
in suspension with small nonadsorbing polymers. The chosen effective one-component …

Ground-state clusters for short-range attractive and long-range repulsive potentials

S Mossa, F Sciortino, P Tartaglia, E Zaccarelli - Langmuir, 2004 - ACS Publications
We report calculations of the ground-state energies and geometries for clusters of different
sizes (up to 80 particles), where individual particles interact simultaneously via a short …

Bovine Serum Albumin protofibril-like aggregates formation: Solo but not simple mechanism

V Vetri, M D'Amico, V Foderà, M Leone… - Archives of biochemistry …, 2011 - Elsevier
We report an experimental study on the model protein Bovine Serum Albumin (BSA), with
the aim of elucidating the mechanisms by which a fully folded globular protein undergoes …

Heat-and pH-induced BSA conformational changes, hydrogel formation and application as 3D cell scaffold

G Navarra, C Peres, M Contardi, P Picone… - Archives of biochemistry …, 2016 - Elsevier
Aggregation and gelation of globular proteins can be an advantage to generate new forms
of nanoscale biomaterials based on the fibrillar architecture. Here, we report results …

Ageing and collapse in gels with long-range attractions

LJ Teece, MA Faers, P Bartlett - Soft Matter, 2011 - pubs.rsc.org
We report measurements on the ageing dynamics of a colloid–polymer mixture with a large
polymer–colloid size ratio of 0.62. Quenched into a two-phase region the system gels and …

[PDF][PDF] Early events in insulin fibrillization studied by time-lapse atomic force microscopy

A Podesta, G Tiana, P Milani, M Manno - Biophysical Journal, 2006 - cell.com
The importance of understanding the mechanism of protein aggregation into insoluble
amyloid fibrils lies not only in its medical consequences, but also in its more basic properties …

Protein stability modulated by a conformational effector: effects of trifluoroethanol on bovine serum albumin

R Carrotta, M Manno, FM Giordano, A Longo… - Physical Chemistry …, 2009 - pubs.rsc.org
The link between the thermodynamic properties of a solution and the conformational space
explored by a protein is of fundamental importance to understand and control solubility …

Irreversible formation of intermediate BSA oligomers requires and induces conformational changes

SM Vaiana, A Emanuele… - Proteins: Structure …, 2004 - Wiley Online Library
Understanding the relation between protein conformational changes and aggregation, and
the physical mechanisms leading to such processes, is of primary importance, due to its …