Validating the distribution of specific ventilation in healthy humans measured using proton MR imaging

RC Sá, AK Asadi, RJ Theilmann… - Journal of Applied …, 2014 - journals.physiology.org
Specific ventilation imaging (SVI) uses proton MRI to quantitatively map the distribution of
specific ventilation (SV) in the human lung, using inhaled oxygen as a contrast agent. To …

Selected discoveries from human research in space that are relevant to human health on Earth

M Shelhamer, J Bloomberg, A LeBlanc, GK Prisk… - npj …, 2020 - nature.com
A substantial amount of life-sciences research has been performed in space since the
beginning of human spaceflight. Investigations into bone loss, for example, are well known; …

Dismantling the pathophysiology of asthma using imaging

GG King, CE Farrow… - European Respiratory …, 2019 - Eur Respiratory Soc
Asthma remains an important disease worldwide, causing high burden to patients and
healthcare systems and presenting a need for better management and ultimately prevention …

Time-based pulmonary features from electrical impedance tomography demonstrate ventilation heterogeneity in chronic obstructive pulmonary disease

S Milne, J Huvanandana, C Nguyen… - Journal of Applied …, 2019 - journals.physiology.org
Pulmonary electrical impedance tomography (EIT) is a functional imaging technique that
allows real-time monitoring of ventilation distribution. Ventilation heterogeneity (VH) is a …

[HTML][HTML] Ventilation/perfusion relationships and gas exchange: measurement approaches

SR Hopkins - Comprehensive Physiology, 2020 - ncbi.nlm.nih.gov
Abstract Ventilation-perfusion (VA/Q) matching, the regional matching of the flow of fresh gas
to flow of deoxygenated capillary blood, is the most important mechanism affecting the …

Peripheral ventilation heterogeneity determines the extent of bronchoconstriction in asthma

CE Farrow, CM Salome, BE Harris… - Journal of applied …, 2017 - journals.physiology.org
In asthma, bronchoconstriction causes topographically heterogeneous airway narrowing, as
measured by three-dimensional ventilation imaging. Computation modeling suggests that …

Motion‐compensated low‐rank reconstruction for simultaneous structural and functional UTE lung MRI

F Tan, X Zhu, M Chan, MA Zapala… - Magnetic resonance …, 2023 - Wiley Online Library
Purpose Three‐dimensional UTE MRI has shown the ability to provide simultaneous
structural and functional lung imaging, but it is limited by respiratory motion and relatively …

Detection of chronic lung allograft dysfunction using ventilation‐weighted Fourier decomposition MRI

A Voskrebenzev, M Greer, M Gutberlet… - American Journal of …, 2018 - Wiley Online Library
Chronic lung allograft dysfunction (CLAD) remains the leading cause of morbidity and
mortality after lung transplantation. Diagnosis requires spirometric change, which becomes …

Reproducibility of fractional ventilation derived by Fourier decomposition after adjusting for tidal volume with and without an MRI compatible spirometer

A Voskrebenzev, M Gutberlet, L Becker… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose To reduce the influence of tidal volume on fractional ventilation (FV) derived by
Fourier decomposition (FD). Methods Twelve volunteers were examined on a 1.5 Tesla …

Vaping disrupts ventilation-perfusion matching in asymptomatic users

AS Kizhakke Puliyakote, AR Elliott… - Journal of Applied …, 2021 - journals.physiology.org
Inhalation of e-cigarette's aerosols (vaping) has the potential to disrupt pulmonary gas
exchange, but the effects in asymptomatic users are unknown. We assessed ventilation …