[HTML][HTML] One is not enough: understanding and modeling polysubstance use
EA Crummy, TJ O'Neal, BM Baskin… - Frontiers in …, 2020 - frontiersin.org
Substance use disorder (SUD) is a chronic, relapsing disease with a highly multifaceted
pathology that includes (but is not limited to) sensitivity to drug-associated cues, negative …
pathology that includes (but is not limited to) sensitivity to drug-associated cues, negative …
Unique, long-term effects of nicotine on adolescent brain
FM Leslie - Pharmacology Biochemistry and Behavior, 2020 - Elsevier
Adolescence is a time of major plasticity of brain systems that regulate motivated behavior
and cognition, and is also the age of peak onset of nicotine use. Although there has been a …
and cognition, and is also the age of peak onset of nicotine use. Although there has been a …
The link between schizophrenia and substance use disorder: A unifying hypothesis
JY Khokhar, LL Dwiel, AM Henricks, WT Doucette… - Schizophrenia …, 2018 - Elsevier
Substance use disorders occur commonly in patients with schizophrenia and dramatically
worsen their overall clinical course. While the exact mechanisms contributing to substance …
worsen their overall clinical course. While the exact mechanisms contributing to substance …
Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function
H Salmanzadeh, SM Ahmadi-Soleimani… - Brain research …, 2020 - Elsevier
Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …
brain development and maturation. The refinement and maturation of the central nervous …
Abuse potential and toxicity of the synthetic cathinones (ie,“Bath salts”)
AL Riley, KH Nelson, P To, R López-Arnau, P Xu… - Neuroscience & …, 2020 - Elsevier
The synthetic cathinones are derived from the naturally occurring drug cathinone found in
the khat plant (Catha edulis) and have chemical structures and neurochemical …
the khat plant (Catha edulis) and have chemical structures and neurochemical …
Mechanisms and genetic factors underlying co-use of nicotine and alcohol or other drugs of abuse
SJ Cross, S Lotfipour, FM Leslie - The American Journal of Drug …, 2017 - Taylor & Francis
Concurrent use of tobacco and alcohol or psychostimulants represents a major public health
concern, with use of one substance influencing consumption of the other. Co-abuse of these …
concern, with use of one substance influencing consumption of the other. Co-abuse of these …
Impact of the aversive effects of drugs on their use and abuse
Drug use and abuse are complex issues in that the basis of each may involve different
determinants and consequences, and the transition from one to the other may be equally …
determinants and consequences, and the transition from one to the other may be equally …
The effects of cannabidiol (CBD) on Δ⁹-tetrahydrocannabinol (THC) self-administration in male and female Long-Evans rats.
AGP Wakeford, BB Wetzell, RL Pomfrey… - Experimental and …, 2017 - psycnet.apa.org
Despite widespread cannabis use in humans, few rodent models exist demonstrating
significant Δ 9-tetrahydrocannabinol (THC) self-administration, possibly due to THC's co …
significant Δ 9-tetrahydrocannabinol (THC) self-administration, possibly due to THC's co …
Sex differences in α-pyrrolidinopentiophenone (α-PVP)-induced taste avoidance, place preference, hyperthermia and locomotor activity in rats
KH Nelson, HN Manke, A Imanalieva, KC Rice… - Pharmacology …, 2019 - Elsevier
Rationale The majority of synthetic cathinone research has used only male subjects, and as
a result there are few studies assessing the impact of biological sex on their effects …
a result there are few studies assessing the impact of biological sex on their effects …
Adolescent nicotine challenge promotes the future vulnerability to opioid addiction: Involvement of lateral paragigantocellularis neurons
Tobacco smoking is recognized as a life-threatening risk factor worldwide. Initiation of
smoking primarily occurs during adolescence which is a critical developmental phase …
smoking primarily occurs during adolescence which is a critical developmental phase …