The 2 most common genetic polymorphisms that predispose to a first episode of venous
thromboembolism (VTE) are factor V Leiden (FVL) and prothrombin G20210A. However, the …

The clinical penetrance of venous thromboembolism (VTE) susceptibility genes is variable,
being lower in heterozygous carriers of factor V Leiden and prothrombin 20210A (mild …

Objective Abacavir, a human immunodeficiency virus-1 (HIV-1) nucleoside-analogue
reverse transcriptase inhibitor, causes severe hypersensitivity in 4–8% of patients. HLA B …

Hypercoagulability due to high coagulation factors XI, VIII, IX, II, and fibrinogen is recognized
as a risk factor of venous thromboembolism (VTE). These factors are cumulatively explored …

Background—The clinical course of cerebral sinus-venous thrombosis (CSVT) is largely
unknown because prospective studies with a long follow-up and with the goal to assess …

Background: Inherited thrombophilia is only weakly associated with recurrence in patients
with a first venous thrombosis (VT). In spite of this, thrombophilia testing is often performed in …

Objectives: Identify the causes of hypercoagulability. Describe the evaluation of a patient
with hypercoagulability. Summarize the treatment of hypercoagulability. Explain modalities …

Thrombophilia can be broadly defined as an increased tendency toward hypercoagulability
and venous thrombosis. There are several defined risk factors for thrombosis, and these are …

Laboratory testing for the identification of heritable thrombophilia in high‐risk patient groups
have become common practice; however, indiscriminate testing of all patients is unjustified …

Deep vein thrombosis is a common disease, with an incidence of one to three per 1000
individuals per year [1]. Numerous risk factors are known, which can be divided into genetic …