Therapeutic potential in rheumatic diseases of extracellular vesicles derived from mesenchymal stromal cells
The incidence of rheumatic diseases such as rheumatoid arthritis and osteoarthritis and
injuries to articular cartilage that lead to osteochondral defects is predicted to rise as a result …
injuries to articular cartilage that lead to osteochondral defects is predicted to rise as a result …
The emerging role of exosomes in innate immunity, diagnosis and therapy
Exosomes, which are nano-sized transport bio-vehicles, play a pivotal role in maintaining
homeostasis by exchanging genetic or metabolic information between different cells …
homeostasis by exchanging genetic or metabolic information between different cells …
Integrated printed BDNF-stimulated HUCMSCs-derived exosomes/collagen/chitosan biological scaffolds with 3D printing technology promoted the remodelling of …
X Liu, J Zhang, X Cheng, P Liu, Q Feng… - Regenerative …, 2023 - academic.oup.com
The restoration of nerve dysfunction after traumatic brain injury (TBI) faces huge challenges
due to the limited self-regenerative abilities of nerve tissues. In situ inductive recovery can …
due to the limited self-regenerative abilities of nerve tissues. In situ inductive recovery can …
Enhancement of the therapeutic efficacy of mesenchymal stem cell-derived exosomes in osteoarthritis
Z Zhang, S Zhao, Z Sun, C Zhai, J Xia, C Wen… - Cellular & Molecular …, 2023 - Springer
Osteoarthritis (OA), a common joint disorder with articular cartilage degradation as the main
pathological change, is the major source of pain and disability worldwide. Despite current …
pathological change, is the major source of pain and disability worldwide. Despite current …
Exosomes derived from mesenchymal stem cells rescue cartilage injury in osteoarthritis through Ferroptosis by GOT1/CCR2 expression
S Peng, C Sun, C Lai, L Zhang - International Immunopharmacology, 2023 - Elsevier
Osteoarthritis is a prevalent joint disease that significantly affects the daily life of the elderly
and is one of the primary causes of disability in this population. This study aims to evaluate …
and is one of the primary causes of disability in this population. This study aims to evaluate …
Osteoarthritis as an umbrella term for different subsets of humans undergoing joint degeneration: The need to address the differences to develop effective …
DA Hart - International Journal of Molecular Sciences, 2022 - mdpi.com
Osteoarthritis (OA) of joints such as the knee and hip are very prevalent, and the number of
individuals affected is expected to continue to rise. Currently, conservative treatments after …
individuals affected is expected to continue to rise. Currently, conservative treatments after …
[HTML][HTML] Innovative therapeutic strategies for cardiovascular disease
K Maiese - EXCLI journal, 2023 - ncbi.nlm.nih.gov
As a significant non-communicable disease, cardiovascular disease is the leading cause of
death for both men and women, comprises almost twenty percent of deaths in most racial …
death for both men and women, comprises almost twenty percent of deaths in most racial …
Combinatorial effect of mesenchymal stem cells and extracellular vesicles in a hydrogel on cartilage regeneration
WJ Cho, J Ahn, M Lee, H Choi, S Park, KY Cha… - Tissue Engineering and …, 2023 - Springer
Abstract Background: Mesenchymal stem cells (MSCs) are used for tissue regeneration due
to their wide differentiation capacity and anti-inflammatory effects. Extracellular vesicles …
to their wide differentiation capacity and anti-inflammatory effects. Extracellular vesicles …
[HTML][HTML] Current status of catabolic, anabolic and inflammatory biomarkers associated with structural and symptomatic changes in the chronic phase of post-traumatic …
Post-traumatic OA (PTOA) can occur within 5 years after a significant injury and is a valuable
paradigm for identifying biomarkers. This systematic review aims to summarise published …
paradigm for identifying biomarkers. This systematic review aims to summarise published …
Strategy insight: Mechanical properties of biomaterials' influence on hydrogel-mesenchymal stromal cell combination for osteoarthritis therapy
H Ying, C Shen, R Pan, X Li, Y Chen - Frontiers in Pharmacology, 2023 - frontiersin.org
Osteoarthritis (OA) is a kind of degenerative joint disease usually found in older adults and
those who have received meniscal surgery, bringing great suffering to a number of patients …
those who have received meniscal surgery, bringing great suffering to a number of patients …