Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …

Circadian clocks are endogenous oscillators that control 24-hour physiological and
behavioural processes in organisms. These cell-autonomous clocks are composed of a …

Circadian clocks coordinate physiology and behavior with the 24h solar day to provide
temporal homeostasis with the external environment. The molecular clocks that drive these …

Context: Shift work, which imposes a habitual disruption in the circadian system, has been
linked to increased incidence of cardiometabolic diseases, and acute circadian …

Stress constitutes a state of threatened homeostasis triggered by intrinsic or extrinsic
adverse forces (stressors) and is counteracted by an intricate repertoire of physiologic and …

Background: There is emerging literature demonstrating a relationship between the timing of
feeding and weight regulation in animals. However, whether the timing of food intake …

The circadian system serves one of the most fundamental properties present in nearly all
organisms: it generates 24-h rhythms in behavioral and physiological processes and …

Circadian rhythms occur in almost all species and control vital aspects of our physiology,
from sleeping and waking to neurotransmitter secretion and cellular metabolism …

Sleep–wake cycles are known to be disrupted in people with neurodegenerative disorders.
These findings are now supported by data from animal models for some of these disorders …

The circadian system of mammals is composed of a hierarchy of oscillators that function at
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …