Signaling pathways and targeted therapy for myocardial infarction
Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022 - nature.com
Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
Angiogenesis after acute myocardial infarction
X Wu, MR Reboll, M Korf-Klingebiel… - Cardiovascular …, 2021 - academic.oup.com
Acute myocardial infarction (MI) inflicts massive injury to the coronary microcirculation
leading to vascular disintegration and capillary rarefication in the infarct region. Tissue …
leading to vascular disintegration and capillary rarefication in the infarct region. Tissue …
Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets
The onset of heart failure is typically preceded by cardiac hypertrophy, a response of the
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …
An injectable conductive hydrogel encapsulating plasmid DNA-eNOs and ADSCs for treating myocardial infarction
Myocardial infarction (MI) leads to the mass death of cardiomyocytes accompanying with the
unfavorable alternation of microenvironment, a fibrosis scar deprived of electrical …
unfavorable alternation of microenvironment, a fibrosis scar deprived of electrical …
A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing In Vivo
The clinical translation of messengerRNA (mRNA) drugs has been slowed by a shortage of
delivery vehicles that potently and safely shuttle mRNA into target cells. Here, we describe …
delivery vehicles that potently and safely shuttle mRNA into target cells. Here, we describe …
Recent development in therapeutic cardiac patches
For the past decades, heart diseases remain the leading cause of death worldwide. In the
adult mammalian heart, damaged cardiomyocytes will be replaced by non-contractile fibrotic …
adult mammalian heart, damaged cardiomyocytes will be replaced by non-contractile fibrotic …
Towards comprehensive cardiac repair and regeneration after myocardial infarction: Aspects to consider and proteins to deliver
Ischemic heart disease is a leading cause of death worldwide. After the onset of myocardial
infarction, many pathological changes take place and progress the disease towards heart …
infarction, many pathological changes take place and progress the disease towards heart …
Cell-based and selected cell-free therapies for myocardial infarction: how do they compare to the current treatment options?
M Csöbönyeiová, N Beerová, M Klein… - International Journal of …, 2022 - mdpi.com
Because of cardiomyocyte death or dysfunction frequently caused by myocardial infarction
(MI), heart failure is a leading cause of morbidity and mortality in modern society …
(MI), heart failure is a leading cause of morbidity and mortality in modern society …
[HTML][HTML] Cardiac regeneration using growth factors: advances and challenges
JS Rebouças, NS Santos-Magalhães… - Arquivos brasileiros de …, 2016 - SciELO Brasil
Myocardial infarction is the most significant manifestation of ischemic heart disease and is
associated with high morbidity and mortality. Novel strategies targeting at regenerating the …
associated with high morbidity and mortality. Novel strategies targeting at regenerating the …
Recent advances in micro/nanoscale biomedical implants
The medical device industry is growing at a very fast pace and has recorded great research
activity over the past decade. The interdisciplinary nature of this field has made it possible …
activity over the past decade. The interdisciplinary nature of this field has made it possible …