[HTML][HTML] Pharmaceutical drugs and natural therapeutic products for the treatment of type 2 diabetes mellitus

J Blahova, M Martiniakova, M Babikova, V Kovacova… - Pharmaceuticals, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is the most widespread form of diabetes, characterized by
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …

[HTML][HTML] Management of diabesity: Current concepts

M Michaelidou, JM Pappachan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
The global prevalence of obesity is increasing rapidly with an exponential rise in incidence
of type 2 diabetes mellitus in recent years.'Diabesity', the term coined to show the strong …

SGLT2-inhibitors are effective and safe in the elderly: The SOLD study

ME Lunati, V Cimino, A Gandolfi, M Trevisan… - Pharmacological …, 2022 - Elsevier
Background and aims Sodium-glucose co-transporter-2 inhibitors (SGLT2i) may have
important benefits for the elderly with type 2 diabetes (T2D), however some safety concerns …

[HTML][HTML] Tirzepatide: A systematic update

I Forzano, F Varzideh, R Avvisato… - International Journal of …, 2022 - mdpi.com
Tirzepatide is a new molecule capable of controlling glucose blood levels by combining the
dual agonism of Glucose-Dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like …

[HTML][HTML] A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus

L Su, C Xin, J Yang, L Dong, H Mei, X Dai… - International Journal of …, 2022 - Elsevier
Type 2 diabetes mellitus is a global disease that endangers human health, and the need for
the development of nontoxic treatment candidates is urgent. In the present work, one …

[HTML][HTML] GLP-1 receptor agonist as a modulator of innate immunity

J Chen, A Mei, Y Wei, C Li, H Qian, X Min… - Frontiers in …, 2022 - frontiersin.org
Glucagon-like peptide-1 (GLP-1) is a 30-amino acid hormone secreted by L cells in the
distal ileum, colon, and pancreatic α cells, which participates in blood sugar regulation by …

[HTML][HTML] A comprehensive review on weight loss associated with anti-diabetic medications

F Haddad, G Dokmak, M Bader, R Karaman - Life, 2023 - mdpi.com
Obesity is a complex metabolic condition that can have a negative impact on one's health
and even result in mortality. The management of obesity has been addressed in a number of …

[HTML][HTML] Sulforaphane: A nutraceutical against diabetes-related complications

SXH Mthembu, SE Mazibuko-Mbeje… - Pharmacological …, 2023 - Elsevier
There is an increasing interest in the use of nutraceuticals and plant-derived bioactive
compounds from foods for their potential health benefits. For example, as a major active …

Tirzepatide reduces the predicted risk of developing type 2 diabetes in people with obesity or overweight: Post hoc analysis of the SURMOUNT‐1 trial

ER Hankosky, H Wang, LM Neff, H Kan… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim We assessed the impact of tirzepatide on 10‐year predicted risk of developing type 2
diabetes (T2D) among participants in the SURMOUNT‐1 trial. Materials and Methods In this …

[HTML][HTML] Comparative effects of nutraceuticals on body weight in adults with overweight or obesity: A systematic review and network meta-analysis of 111 randomized …

H Shahinfar, A Jayedi, K Torabynasab… - Pharmacological …, 2023 - Elsevier
There is no research on the comparative effects of nutraceuticals on weight loss in adults
with overweight or obesity. This study aimed at quantifying and ranking the effects of …