Nanocarrier-Mediated Drug Delivery via Inhalational Route for Lung Cancer Therapy: A Systematic and Updated Review

N Ara, A Hafeez - AAPS PharmSciTech, 2024 - Springer
Lung cancer is one of the most severe lethal malignancies, with approximately 1.6 million
deaths every year. Lung cancer can be broadly categorised into small and non-small-cell …

An overview of the efficacy of inhaled curcumin: a new mode of administration for an old molecule

N Rastegar-Pouyani, TS Dongsar, M Ataei… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Curcumin is a polyphenol with a variety of pharmacological actions. Despite its
therapeutic effects and well-known safety profile, the utility of curcumin has been limited due …

Pulmonary delivery of curcumin and quercetin nanoparticles for lung cancer–Part 1: aerosol performance characterization

CY Loo, D Traini, PM Young, T Parumasivam… - Journal of Drug Delivery …, 2023 - Elsevier
Pulmonary delivery could be an effective method to provide higher dose of
chemotherapeutic drugs onto the lung as well as minimize systemic toxicity. In this study …

A drug co-delivery platform made of magnesium-based micromotors enhances combination therapy for hepatoma carcinoma cells

Q Song, Y Liu, X Ding, M Feng, J Li, W Liu, B Wang… - Nanoscale, 2023 - pubs.rsc.org
Combination therapy is an emerging strategy to overcome multidrug resistance (MDR) in
hepatocellular carcinoma (HCC) chemotherapy treatment. However, the passive diffusion in …

Fabrication of polyphenol nanoparticles co-stabilized with different polyvinylpyrrolidone concentrations: effects on particle stability, drug release and cellular uptake

CY Loo, C Gnanaraj, D Traini, PM Young… - Journal of Drug Delivery …, 2023 - Elsevier
Curcumin (CUR) and quercetin (QUE) possess low stability owing to their limited solubility in
physiological conditions, and hence low bioavailability. This study evaluated …

Quercetin and its nanoformulations as promising agents for lung cancer treatment: A focus on molecular mechanisms

R Arefnezhad, SS Amin, A Mohammdi… - Journal of Drug Delivery …, 2024 - Elsevier
Lung cancer is described as the main reason for death pertinent to cancer in subjects
aged≥ 50 years, and metastasis has a pivotal role in its lethality. This life-threatening …

Exploring the current advancements of quercetin nanoformulations alleviating respiratory diseases

S Yeung, KR Paudel, GD Rubis… - Future Medicinal …, 2024 - Taylor & Francis
Respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD) and
lung cancer place an immense global burden, not only on the quality of life of patients but …

Exploring the Role of Curcumin in Cancer: A Long Road Ahead

P Tiwary, K Oswal, D Kumar - 2023 - Springer
Curcumin is a natural compound that is extracted from the rhizomes of Curcuma longa, also
known as turmeric. Its bright yellow color and hydrophobic nature make it a unique …