ErbB targeted drugs and angiogenesis
E Iivanainen, K Elenius - Current vascular pharmacology, 2010 - ingentaconnect.com
Members of the ErbB receptor tyrosine kinase family are central regulators of several normal
as well as tumor cell functions. A number of therapeutic compounds such as small molecular …
as well as tumor cell functions. A number of therapeutic compounds such as small molecular …
Proteomics and non-proteomics approaches to study stable and transient protein-protein interactions
AG Ngounou Wetie, I Sokolowska… - Advancements of Mass …, 2019 - Springer
Abstract Of the 25,000–30,000 human genes, about 2% code for proteins. However, there
are about 1-2 million protein entities. This is primarily due to alternative splicing, post …
are about 1-2 million protein entities. This is primarily due to alternative splicing, post …
Evolving lipid-based delivery systems in the management of neoplastic disease
I Shapira, DR Budman, T Bradley, R Gralla - Oncology Reviews, 2009 - Springer
Drug delivery systems for the therapeutic use of cytotoxic chemotherapy are an essential
aspect of successful treatment and remain under active evaluation. Such systems offer …
aspect of successful treatment and remain under active evaluation. Such systems offer …
EGFR targeted nanocarriers for cancer diagnosis and therapy
Conventional cancer management is directly associated with many problems, including
accurate therapeutic delivery to tumours and serious side effects of chemotherapeutics. A …
accurate therapeutic delivery to tumours and serious side effects of chemotherapeutics. A …
Nimotuzumab combined with chemoradiotherapy for the treatment of cervical cancer: A meta-analysis of randomized controlled trials
Y Yuan, J Chen, M Fang, Y Guo, X Sun, D Yu… - Frontiers in …, 2022 - frontiersin.org
Objectives To assess the clinical efficacy and toxicity of nimotuzumab in combination with
chemoradiotherapy or chemoradiotherapy alone in the treatment of cervical cancer …
chemoradiotherapy or chemoradiotherapy alone in the treatment of cervical cancer …
The use of protein array to identify targetable receptor tyrosine kinases for treatment of human colon cancer
A Morishita, J Gong, T Nomura… - International …, 2010 - spandidos-publications.com
Several studies have reported that activated receptor tyrosine kinases (RTKs) are highly
expressed in colon cancer and may promote tumor growth and survival. However, there is …
expressed in colon cancer and may promote tumor growth and survival. However, there is …
[PDF][PDF] Characterization of a novel, trastuzumab resistant human breast cancer cell line
[Frontiers in Bioscience E2, 627-640, January 1, 2010] 627 Characterization of a novel,
trastuzumab resistant human breast cance Page 1 [Frontiers in Bioscience E2, 627-640, January …
trastuzumab resistant human breast cance Page 1 [Frontiers in Bioscience E2, 627-640, January …
Structure of the Fab fragment of the anti-murine EGFR antibody 7A7 and exploration of its receptor binding site
A Talavera, J Mackenzie, G Garrido, R Friemann… - Molecular …, 2011 - Elsevier
The EGF receptor is an important target of cancer immunotherapies. The 7A7 monoclonal
antibody has been raised against the murine EGFR, but it cross-reacts with the human …
antibody has been raised against the murine EGFR, but it cross-reacts with the human …
From antibodies to living drugs: Quo vadis cancer immunotherapy?
In the last few decades, monoclonal antibodies targeting various receptors and ligands have
shown significant advance in cancer therapy. However, still a great percentage of patients …
shown significant advance in cancer therapy. However, still a great percentage of patients …