[HTML][HTML] Neutrophils and COVID-19: The road so far
LHA Cavalcante-Silva, DCM Carvalho… - International …, 2021 - Elsevier
The SARS-Cov2 infection triggers a multisystem inflammatory disorder, knowing as COVID-
19, a pandemic disease. This disease is characterized by acute respiratory distress …
19, a pandemic disease. This disease is characterized by acute respiratory distress …
The role of macrophages in the development of acute and chronic inflammatory lung diseases
JW Lee, W Chun, HJ Lee, JH Min, SM Kim, JY Seo… - Cells, 2021 - mdpi.com
Macrophages play an important role in the innate and adaptive immune responses of organ
systems, including the lungs, to particles and pathogens. Cumulative results show that …
systems, including the lungs, to particles and pathogens. Cumulative results show that …
The role of neutrophil extracellular traps in acute lung injury
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …
morbidity and mortality. Neutrophils play a key role in the development of different forms of …
Oxidative stress and inflammation in acute and chronic lung injuries
FS Bezerra, M Lanzetti, RT Nesi, AC Nagato, CP Silva… - Antioxidants, 2023 - mdpi.com
Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …
injury can affect several components of the respiratory system, including the airways …
[PDF][PDF] The vascular perspective on acute and chronic lung disease
I Borek, A Birnhuber, NF Voelkel… - Journal of Clinical …, 2023 - Am Soc Clin Investig
The pulmonary vasculature has been frequently overlooked in acute and chronic lung
diseases, such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis (PF), and …
diseases, such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis (PF), and …
Selective activation of PFKL suppresses the phagocytic oxidative burst
In neutrophils, nicotinamide adenine dinucleotide phosphate (NADPH) generated via the
pentose phosphate pathway fuels NADPH oxidase NOX2 to produce reactive oxygen …
pentose phosphate pathway fuels NADPH oxidase NOX2 to produce reactive oxygen …
The role of cytokines in neutrophil development, tissue homing, function and plasticity in health and disease
M Tsioumpekou, D Krijgsman, JHW Leusen… - Cells, 2023 - mdpi.com
Neutrophils are crucial innate immune cells and comprise 50–70% of the white blood cell
population under homeostatic conditions. Upon infection and in cancer, blood neutrophil …
population under homeostatic conditions. Upon infection and in cancer, blood neutrophil …
Role of neutrophil extracellular traps in health and disease pathophysiology: recent insights and advances
MM Islam, N Takeyama - International Journal of Molecular Sciences, 2023 - mdpi.com
Neutrophils are the principal trouper of the innate immune system. Activated neutrophils
undergo a noble cell death termed NETosis and release a mesh-like structure called …
undergo a noble cell death termed NETosis and release a mesh-like structure called …
A new immortalized human alveolar epithelial cell model to study lung injury and toxicity on a breathing lung-on-chip system
A Sengupta, N Roldan, M Kiener, L Froment… - Frontiers in …, 2022 - frontiersin.org
The evaluation of inhalation toxicity, drug safety and efficacy assessment, as well as the
investigation of complex disease pathomechanisms, are increasingly relying on in vitro lung …
investigation of complex disease pathomechanisms, are increasingly relying on in vitro lung …