[HTML][HTML] The immune microenvironment in cartilage injury and repair

M Li, H Yin, Z Yan, H Li, J Wu, Y Wang, F Wei, G Tian… - Acta Biomaterialia, 2022 - Elsevier
The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

Repair of damaged articular cartilage: current approaches and future directions

EV Medvedeva, EA Grebenik, SN Gornostaeva… - International journal of …, 2018 - mdpi.com
Articular hyaline cartilage is extensively hydrated, but it is neither innervated nor
vascularized, and its low cell density allows only extremely limited self-renewal. Most clinical …

A 3D-printed PRP-GelMA hydrogel promotes osteochondral regeneration through M2 macrophage polarization in a rabbit model

G Jiang, S Li, K Yu, B He, J Hong, T Xu, J Meng, C Ye… - Acta biomaterialia, 2021 - Elsevier
Osteochondral regeneration is an orchestrated process of inflammatory immunity, host cell
response, and implant degradation in tissue engineering. Here, the effects of a platelet-rich …

Platelet-rich plasma (PRP) in osteoarthritis (OA) knee: correct dose critical for long term clinical efficacy

H Bansal, J Leon, JL Pont, DA Wilson, A Bansal… - Scientific reports, 2021 - nature.com
Despite encouraging results reported with regards to Platelet-rich plasma (PRP) application
in osteoarthritis (OA) knee, still critical issues like conclusive structural evidence of its …

[HTML][HTML] Mesenchymal stem cell-loaded thermosensitive hydroxypropyl chitin hydrogel combined with a three-dimensional-printed poly (ε-caprolactone)/nano …

X Ji, X Yuan, L Ma, B Bi, H Zhu, Z Lei, W Liu, HX Pu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Chitin-derived hydrogels are commonly used in bone regeneration because of their high cell
compatibility; however, their poor mechanical properties and little knowledge of the …

[HTML][HTML] Down-regulated ciRS-7/up-regulated miR-7 axis aggravated cartilage degradation and autophagy defection by PI3K/AKT/mTOR activation mediated by IL …

X Zhou, J Li, Y Zhou, Z Yang, H Yang, D Li… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is one of the most painful and widespread chronic degenerative joint
diseases and is characterized by destructed articular cartilage and inflamed joints …

Zwitterionic granular hydrogel for cartilage tissue engineering

M Asadikorayem, F Surman, P Weber… - Advanced …, 2023 - Wiley Online Library
Zwitterionic hydrogels have high potential for cartilage tissue engineering due to their ultra‐
hydrophilicity, nonimmunogenicity, and superior antifouling properties. However, their …

Biomedical applications of nanoceria: new roles for an old player

S Kargozar, F Baino, SJ Hoseini, S Hamzehlou… - …, 2018 - Taylor & Francis
The use of different biomaterials with the ability to accelerate the repair and regeneration
processes is of great importance in tissue engineering strategies. On this point, cerium oxide …

Platelet-rich plasma and cartilage repair

MI Kennedy, K Whitney, T Evans… - Current reviews in …, 2018 - Springer
Abstract Purpose of Review To assess the utilization and efficacy of platelet-rich plasma
(PRP), for the treatment of articular cartilage injury, most commonly characterized by …

Inflammation-modulating hydrogels for osteoarthritis cartilage tissue engineering

RH Koh, Y Jin, J Kim, NS Hwang - Cells, 2020 - mdpi.com
Osteoarthritis (OA) is the most common form of the joint disease associated with age,
obesity, and traumatic injury. It is a disabling degenerative disease that affects synovial …