NADPH oxidases: from molecular mechanisms to current inhibitors

A Cipriano, M Viviano, A Feoli, C Milite… - Journal of medicinal …, 2023 - ACS Publications
NADPH oxidases (NOXs) form a family of electron-transporting membrane enzymes whose
main function is reactive oxygen species (ROS) generation. Strong evidence suggests that …

Roles of non-coding RNA in alzheimer's disease pathophysiology

EO Olufunmilayo, RMD Holsinger - International journal of molecular …, 2023 - mdpi.com
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is accompanied by
deficits in memory and cognitive functions. The disease is pathologically characterised by …

Alzheimer's disease and green tea: epigallocatechin-3-gallate as a modulator of inflammation and oxidative stress

V Valverde-Salazar, D Ruiz-Gabarre… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia, characterised by a
marked decline of both memory and cognition, along with pathophysiological hallmarks …

Engineered exosome for drug delivery: recent development and clinical applications

J Tian, Z Han, D Song, Y Peng, M Xiong… - International Journal …, 2023 - Taylor & Francis
Exosomes are nano-sized membrane vesicles that transfer bioactive molecules between
cells and modulate various biological processes under physiological and pathological …

Effects of DHA on cognitive dysfunction in aging and Alzheimer's disease: The mediating roles of ApoE

X Zhang, T Yuan, X Chen, X Liu, J Hu, Z Liu - Progress in Lipid Research, 2023 - Elsevier
The prevalence of Alzheimer's disease (AD) continues to rise due to the increasing aging
population. Among the various genetic factors associated with AD, apolipoprotein E (ApoE) …

Improving cognitive function with nutritional supplements in aging: a comprehensive narrative review of clinical studies investigating the effects of vitamins, minerals …

M Fekete, A Lehoczki, S Tarantini, V Fazekas-Pongor… - Nutrients, 2023 - mdpi.com
Cognitive impairment and dementia are burgeoning public health concerns, especially
given the increasing longevity of the global population. These conditions not only affect the …

Neuroprotective effects of carnosic acid: Insight into its mechanisms of action

FJ Mirza, S Zahid, RMD Holsinger - Molecules, 2023 - mdpi.com
Carnosic acid is a diterpenoid abundantly present in plants belonging to the genus
Rosmarinus and Salvia of the family Lamiaceae, accounting for their application in …

The Role of Hydrogen Sulfide (H2S) in Epigenetic Regulation of Neurodegenerative Diseases: A Systematic Review

BG Dogaru, C Munteanu - International Journal of Molecular Sciences, 2023 - mdpi.com
This review explores the emerging role of hydrogen sulfide (H2S) in modulating epigenetic
mechanisms involved in neurodegenerative diseases. Accumulating evidence has begun to …

Reverse electron transport at mitochondrial complex I in ischemic stroke, aging, and age-related diseases

V Chavda, B Lu - Antioxidants, 2023 - mdpi.com
Stroke is one of the leading causes of morbidity and mortality worldwide. A main cause of
brain damage by stroke is ischemia-reperfusion (IR) injury due to the increased production …

[HTML][HTML] The bioavailability, health advantages, extraction method, and distribution of free and bound phenolics of rice, wheat, and maize: A review

R Sahu, S Mandal, P Das, GJ Ashraf, TK Dua… - Food Chemistry …, 2023 - Elsevier
One of the primary sources of human sustenance is cereal grains, and the production of
these grains has expanded recently to meet the demands of the growing global population …