Background Rheumatoid arthritis (RA) is an autoimmune disease that underlies chronic
inflammation of the synovial membrane. Non-steroidal anti-inflammatory drugs (NSAIDs) are …

Raloxifene HCl belongs to a class of selective estrogen receptor modulators (SERMs) which
is used for the management of breast cancer. The major problem reported with raloxifene is …

The low aqueous solubility and permeability of apremilast restricted its clinical efficiency in
oral therapy for psoriasis arthritis. This research aimed to develop nanosized lipid carrier …

The aim of the current study was to develop the phytosomal gel of aloe vera extract for
improved topical delivery. Aloe vera extract loaded phytosomal system was developed by …

This study aimed to formulate suitable nanovesicles (NVs) for transdermal delivery of
Ondansetron. It also illustrated a practical example for the importance of Box-Cox …

Pain and inflammation could have a negative impact on a patient's quality of life and
performance, causing them to sleep less. Dexketoprofen trometamol (DKT) is a water …

The primary objective of this study was to develop, evaluate and compare the effectiveness
and stability of ethosomal carbomer gels in different solvents. The optimal ethosomal …

Poor bioavailability of drugs via oral route is the greatest challenge facing drug formulation.
To overcome this obstacle, transdermal route was commonly used as an alternative route to …

This study was intended to develop and optimize agomelatine loaded lipid-based
transdermal vesicles (AGLTVs) for the treatment of depression. For the optimization purpose …

The beta-adrenoceptor blocker timolol maleate (TML) is a commonly used pharmaceutical
agent for the management of glaucoma. Conventional eye drops have limitations due to …