Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD), previously
described as Parkinsonian syndromes are also cognitive disorders, and biologically related …

The presence of cognitive impairment in corticobasal degeneration (CBD) is now widely
recognised. Our review of the literature reveals that, although the pattern and severity of …

Neurofibrillary tangles are a characteristic hallmark of Alzheimer's and other
neurodegenerative diseases, such as Pick's disease (PiD), progressive supranuclear palsy …

The risk of developing tauopathic neurodegenerative disease depends in part on the levels
and composition of six naturally occurring Tau isoforms in human brain. These proteins …

Neurofibrillary tangles composed of exon 10+ microtubule associated protein tau (MAPT)
deposits are the characteristic feature of the neurodegenerative diseases progressive …

Diagnostic accuracy has been addressed previously for Parkinson's disease in a brain bank
collection, but accuracy of progressive supranuclear palsy (PSP) has not been addressed in …

Two extended haplotypes exist across the tau gene—H1 and H2—with H1 consistently
associated with increased risk of progressive supranuclear palsy (PSP). Using 15 haplotype …

There are 6 different isoforms of tau expressed in the adult human brain, and little
information is available on the cellular distribution of the isoforms. Tau inclusions are found …

Argyrophilic grain disease (AgD) is a late‐onset dementia morphologically characterized by
the presence of abundant spindle‐shaped argyrophilic grains (ArG) in neuronal processes …

Olfactory dysfunction increases with disease severity in Alzheimer's disease (AD), is early
and independent of disease severity in Parkinson's disease (PD), but is absent in …