The technology, opportunities and challenges of synthetic biological intelligence
Integrating neural cultures developed through synthetic biology methods with digital
computing has enabled the early development of Synthetic Biological Intelligence (SBI) …
computing has enabled the early development of Synthetic Biological Intelligence (SBI) …
[HTML][HTML] Patient-derived organoids in translational oncology and drug screening
R Yang, Y Yu - Cancer Letters, 2023 - Elsevier
Patient-derived organoids (PDO) are a new biomedical research model that can reconstruct
phenotypic and genetic characteristics of the original tissue and are useful for research on …
phenotypic and genetic characteristics of the original tissue and are useful for research on …
[HTML][HTML] Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish
Biological computing (or biocomputing) offers potential advantages over silicon-based
computing in terms of faster decision-making, continuous learning during tasks, and greater …
computing in terms of faster decision-making, continuous learning during tasks, and greater …
Organoid intelligence (OI)–the ultimate functionality of a brain microphysiological system
Understanding brain function remains challenging as work with human and animal models
is complicated by compensatory mechanisms, while in vitro models have been too simple …
is complicated by compensatory mechanisms, while in vitro models have been too simple …
The promise and potential of brain organoids
L Smirnova, T Hartung - Advanced Healthcare Materials, 2024 - Wiley Online Library
Brain organoids are 3D in vitro culture systems derived from human pluripotent stem cells
that self‐organize to model features of the (developing) human brain. This review examines …
that self‐organize to model features of the (developing) human brain. This review examines …
Revisiting the role of HR in the age of AI: bringing humans and machines closer together in the workplace
The functions of human resource management (HRM) have changed radically in the past 20
years due to market and technological forces, becoming more cross-functional and data …
years due to market and technological forces, becoming more cross-functional and data …
Microinstrumentation for brain organoids
D Patel, S Shetty, C Acha, IEM Pantoja… - Advanced …, 2024 - Wiley Online Library
Brain organoids are three‐dimensional aggregates of self‐organized differentiated stem
cells that mimic the structure and function of human brain regions. Organoids bridge the …
cells that mimic the structure and function of human brain regions. Organoids bridge the …
Asteroid impact: the potential of astrocytes to modulate human neural networks within organoids
SS Lavekar, MD Patel, MD Montalvo-Parra… - Frontiers in …, 2023 - frontiersin.org
Astrocytes are a vital cellular component of the central nervous system that impact neuronal
function in both healthy and pathological states. This includes intercellular signals to …
function in both healthy and pathological states. This includes intercellular signals to …
Brain organoids: are they for real?
R Quirion - Frontiers in Science, 2023 - frontiersin.org
In 1965, Gordon E. Moore, the co-founder of Intel, observed that the number of transistors on
a single microchip doubles approximately every two years, while the cost of computers …
a single microchip doubles approximately every two years, while the cost of computers …
Versatile micro-electrode array to monitor human iPSC derived 3D neural tissues at air-liquid interface
L Stoppini, MO Heuschkel, C Loussert-Fonta… - Frontiers in Cellular …, 2024 - frontiersin.org
Engineered 3D neural tissues made of neurons and glial cells derived from human induced
pluripotent stem cells (hiPSC) are among the most promising tools in drug discovery and …
pluripotent stem cells (hiPSC) are among the most promising tools in drug discovery and …