This review provides an introduction to two eyetracking measures that can be used to study
cognitive development and plasticity: pupil dilation and spontaneous blink rate. We begin by …

This review aims to synthesise a large pre-clinical and clinical literature related to a
hypothesised role of the locus coeruleus norepinephrine system in responses to acute and …

Attention is critical to high-level cognition and attention deficits are a hallmark of neurologic
and neuropsychiatric disorders. Although years of research indicates that distinct …

Many aspects of cognition and behaviour are regulated by noradrenergic projections to the
forebrain originating from the locus coeruleus, acting through alpha and beta …

Vagus nerve stimulation (VNS) is widely used to treat drug-resistant epilepsy and
depression. While the precise mechanisms mediating its long-term therapeutic effects are …

“A rigorous, in-depth guide to the history, philosophy, and scientific exploration of this
widespread emotional state...[LeDoux] offers a magisterial review of the role of mind and …

Many emotional stimuli are processed without being consciously perceived. Recent
evidence indicates that subcortical structures have a substantial role in this processing …

Historically, the locus coeruleus-norepinephrine (LC-NE) system has been implicated in
arousal, but recent findings suggest that this system plays a more complex and specific role …

Sleep is characterized by synchronized events in billions of synaptically coupled neurons in
thalamocortical systems. The activation of a series of neuromodulatory transmitter systems …

The adaptive gain theory highlights the pivotal role of the locus coeruleus–noradrenergic
(LC‐NE) system in regulating task engagement. In humans, however, LC‐NE functional …