The role of the host—Neutrophil biology

ILC Chapple, J Hirschfeld, A Kantarci… - Periodontology …, 2023 - Wiley Online Library
Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with
lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial …

Neutrophils—from bone marrow to first-line defense of the innate immune system

RF Kraus, MA Gruber - Frontiers in immunology, 2021 - frontiersin.org
Neutrophils (polymorphonuclear cells; PMNs) form a first line of defense against pathogens
and are therefore an important component of the innate immune response. As a result of …

Inflammation-mediated matrix remodeling of extracellular matrix-mimicking biomaterials in tissue engineering and regenerative medicine

M Xu, T Su, X Jin, Y Li, Y Yao, K Liu, K Chen, F Lu… - Acta Biomaterialia, 2022 - Elsevier
Extracellular matrix (ECM)-mimicking biomaterials are considered effective tissue-
engineered scaffolds for regenerative medicine because of their biocompatibility …

Pulmonary hypertension: Linking inflammation and pulmonary arterial stiffening

SF Liu, N Nambiar Veetil, Q Li… - Frontiers in …, 2022 - frontiersin.org
Pulmonary hypertension (PH) is a progressive disease that arises from multiple etiologies
and ultimately leads to right heart failure as the predominant cause of morbidity and …

NETosis promotes chronic inflammation and fibrosis in systemic lupus erythematosus and COVID-19

H Lin, J Liu, N Li, B Zhang, P Yao, J Feng, Q Liu… - Clinical …, 2023 - Elsevier
Pulmonary fibrosis, a serious complication of systemic lupus erythematosus (SLE) and
coronavirus disease 2019 (COVID-19), leads to irreversible lung damage. However, the …

Neutrophil extracellular traps in asthma: friends or foes?

R Poto, M Shamji, G Marone, SR Durham… - Cells, 2022 - mdpi.com
Asthma is a chronic inflammatory disease characterized by variable airflow limitation and
airway hyperresponsiveness. A plethora of immune and structural cells are involved in …

Autophagy in extracellular matrix and wound healing modulation in the cornea

D Kempuraj, RR Mohan - Biomedicines, 2022 - mdpi.com
Autophagy is a robust cellular mechanism for disposing of harmful molecules or recycling
them to cells, which also regulates physiopathological processes in cornea. Dysregulated …

Leveling up the controversial role of neutrophils in cancer: when the complexity becomes entangled

RV Sionov - Cells, 2021 - mdpi.com
Neutrophils are the most abundant immune cell in the circulation of human and act as
gatekeepers to discard foreign elements that have entered the body. They are essential in …

Association of immune cell recruitment and BPD development

M Heydarian, C Schulz, T Stoeger… - Molecular and Cellular …, 2022 - Springer
In the neonatal lung, exposure to both prenatal and early postnatal risk factors converge into
the development of injury and ultimately chronic disease, also known as bronchopulmonary …

The emerging role of immune cells and targeted therapeutic strategies in diabetic wounds healing

J Song, L Hu, B Liu, N Jiang, H Huang… - Journal of …, 2022 - Taylor & Francis
Poor wound healing in individuals with diabetes has long plagued clinicians, and immune
cells play key roles in the inflammation, proliferation and remodeling that occur in wound …