Solid lipid nanoparticles (SLNs): an advanced drug delivery system targeting brain through BBB

MK Satapathy, TL Yen, JS Jan, RD Tang, JY Wang… - Pharmaceutics, 2021 - mdpi.com
The blood–brain barrier (BBB) plays a vital role in the protection and maintenance of
homeostasis in the brain. In this way, it is an interesting target as an interface for various …

Marine algae-derived bioactive compounds: a new wave of nanodrugs?

F Menaa, U Wijesinghe, G Thiripuranathar… - Marine drugs, 2021 - mdpi.com
Marine algae are rich in bioactive nutraceuticals (eg, carbohydrates, proteins, minerals, fatty
acids, antioxidants, and pigments). Biotic (eg, plants, microorganisms) and abiotic factors …

Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation

Y Shou, L Yang, Y Yang, J Xu - Cell death & disease, 2021 - nature.com
Psoriasis is a common, chronic, and recurrent inflammatory disease. It is characterized by
hyperproliferation and abnormal differentiation of keratinocytes. Keratinocyte death is also …

Oxidative stress in Alzheimer's disease

Z Chen, C Zhong - Neuroscience bulletin, 2014 - Springer
Oxidative stress plays a significant role in the pathogenesis of Alzheimer's disease (AD), a
devastating disease of the elderly. The brain is more vulnerable than other organs to …

Cannabidiol as a therapeutic target: evidence of its neuroprotective and neuromodulatory function in Parkinson's disease

F Patricio, AA Morales-Andrade… - Frontiers in …, 2020 - frontiersin.org
The phytocannabinoids of Cannabis sativa L. have, since ancient times, been proposed as a
pharmacological alternative for treating various central nervous system (CNS) disorders …

Microwave-assisted extraction of flavonoids: a review

W Routray, V Orsat - Food and Bioprocess Technology, 2012 - Springer
Flavonoids are major bioactive compounds known to be beneficial against many chronic
diseases such as cancer, cardiovascular disorders, and inflammation. Food products …

Neurodegenerative diseases and oxidative stress

KJ Barnham, CL Masters, AI Bush - Nature reviews Drug discovery, 2004 - nature.com
Oxidative stress has been implicated in the progression of Alzheimer's disease, Parkinson's
disease and amyotrophic lateral sclerosis. Oxygen is vital for life but is also potentially …

Oxidative stress and neurodegeneration: where are we now?

B Halliwell - Journal of neurochemistry, 2006 - Wiley Online Library
The brain and nervous system are prone to oxidative stress, and are inadequately equipped
with antioxidant defense systems to prevent 'ongoing'oxidative damage, let alone the extra …

Gold Nanorods with Spatial Separation of CeO2 Deposition for Plasmonic-Enhanced Antioxidant Stress and Photothermal Therapy of Alzheimer's Disease

K Ge, Y Mu, M Liu, Z Bai, Z Liu, D Geng… - ACS Applied Materials …, 2022 - ACS Publications
Activities of catalase (CAT) and superoxide dismutase (SOD) of ceria nanoparticles (CeO2
NPs) provide the possibility for their application in nervous system oxidative stress diseases …

Iron, brain ageing and neurodegenerative disorders

L Zecca, MBH Youdim, P Riederer, JR Connor… - Nature Reviews …, 2004 - nature.com
There is increasing evidence that iron is involved in the mechanisms that underlie many
neurodegenerative diseases. Conditions such as neuroferritinopathy and Friedreich ataxia …