Role of gonadally synthesized steroid hormones in the colorectal cancer microenvironment
L Wenxuan, L Liu, L Zhang, Z Qiu, Z Wu… - Frontiers in …, 2023 - frontiersin.org
Objective To understand the relationship between steroid hormones synthesized by the
gonads and colorectal cancer as well as its tumor microenvironment, in the expectation of …
gonads and colorectal cancer as well as its tumor microenvironment, in the expectation of …
[HTML][HTML] Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males
Although ovarian sex steroids could have protective roles against colorectal cancer (CRC) in
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …
New Insights on the Progesterone (P4) and PGRMC1/NENF Complex Interactions in Colorectal Cancer Progression
J Kamińska, OM Koper-Lenkiewicz… - Cancers, 2023 - mdpi.com
Simple Summary Progesterone (P4) via PGRMC1/NENF may stimulate the proliferation and
invasion of colorectal cancer DLD-1 and HT-29 cells. PGRMC1 inhibition abolishes the …
invasion of colorectal cancer DLD-1 and HT-29 cells. PGRMC1 inhibition abolishes the …
[HTML][HTML] Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness
Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …
Progesterone suppresses the progression of colonic carcinoma by increasing the activity of the GADD45α/JNK/c‑Jun signalling pathway
YL Zhang, XD Wen, X Guo, SQ Huang… - Oncology …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most diagnosed cancer worldwide. Progesterone is
associated with a decreased risk of CRC and leads to a favourable prognosis. However, the …
associated with a decreased risk of CRC and leads to a favourable prognosis. However, the …
Therapeutic strategies and potential actions of female sex steroid hormones and their receptors in Colon cancer based on preclinical studies
AA Mahbub - Life, 2022 - mdpi.com
Several epidemiological studies have reported that the use of female sex steroid hormones
could reduce the risk of colon cancer (CRC). This review summarizes the available data …
could reduce the risk of colon cancer (CRC). This review summarizes the available data …
Diagnostic and prognostic impact of progesterone receptor immunohistochemistry: a study evaluating more than 16,000 tumors
F Viehweger, LM Tinger, D Dum… - Analytical Cellular …, 2022 - Wiley Online Library
Progesterone receptor (PR) is a member of the nuclear/steroid hormone receptor family of
ligand‐dependent transcription factors. It plays an important role in reproduction and …
ligand‐dependent transcription factors. It plays an important role in reproduction and …
[PDF][PDF] Neutrophil To Lymphocyte Ratio As A Predictor Of Severity In Colorectal Adenocarcinoma.
S Ali, S Shahab, M Rauf, SK Riaz… - Journal of Ayub …, 2022 - academia.edu
Background: Colorectal cancers are slowly developing cancers of which more than 95% are
adenocarcinomas, beginning in the mucus-producing glands lining the colon and rectum. In …
adenocarcinomas, beginning in the mucus-producing glands lining the colon and rectum. In …
[HTML][HTML] Attenuation of rat colon carcinogenesis by Styela plicata aqueous extract. modulation of NF-κB pathway and cytoplasmic Sod1 gene expression
Objective: In search for a unique natural combination of highly active biological components
for treatment against colon cancer, we used aqueous extract of Ascidia, Styela plicata …
for treatment against colon cancer, we used aqueous extract of Ascidia, Styela plicata …
[PDF][PDF] Background: Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR) receptors are pathologically altered in colorectal cancer (CRC), their …
VK Pidugu, S Ramadesikan, A Kulkarni, H Makala… - 2023 - academia.edu
Background: Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …