Objective To understand the relationship between steroid hormones synthesized by the
gonads and colorectal cancer as well as its tumor microenvironment, in the expectation of …

Although ovarian sex steroids could have protective roles against colorectal cancer (CRC) in
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …

Simple Summary Progesterone (P4) via PGRMC1/NENF may stimulate the proliferation and
invasion of colorectal cancer DLD-1 and HT-29 cells. PGRMC1 inhibition abolishes the …

Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …

Colorectal cancer (CRC) is the third most diagnosed cancer worldwide. Progesterone is
associated with a decreased risk of CRC and leads to a favourable prognosis. However, the …

Several epidemiological studies have reported that the use of female sex steroid hormones
could reduce the risk of colon cancer (CRC). This review summarizes the available data …

Progesterone receptor (PR) is a member of the nuclear/steroid hormone receptor family of
ligand‐dependent transcription factors. It plays an important role in reproduction and …

Background: Colorectal cancers are slowly developing cancers of which more than 95% are
adenocarcinomas, beginning in the mucus-producing glands lining the colon and rectum. In …

Objective: In search for a unique natural combination of highly active biological components
for treatment against colon cancer, we used aqueous extract of Ascidia, Styela plicata …

Background: Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …