The spike protein (S) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
required for cell entry and is the primary focus for vaccine development. In this study, we …

Until fairly recently, genome-wide evolutionary dynamics and within-host diversity were
more commonly examined in the context of small viruses than in the context of large double …

Small‐scale sequencing has improved substantially in recent decades, culminating in the
development of next‐generation sequencing (NGS) technologies. Modern NGS methods …

Motivation High-throughput sequencing technologies are used increasingly not only in viral
genomics research but also in clinical surveillance and diagnostics. These technologies …

Background Next-generation sequencing (NGS) allows ultra-deep sequencing of nucleic
acids. The use of sequence-independent amplification of viral nucleic acids without …

A single-cycle herpes simplex virus (HSV) deleted in glycoprotein D (ΔgD-2) elicited high
titer HSV-specific antibodies (Abs) that (i) were rapidly transported into the vaginal …

Metagenomic gene classifications are significant in bioinformatics and computational
biology research. There are huge interrelated datasets that deal with human characteristics …

Phages infecting Aeromonas salmonicida subsp. salmonicida, the causative agent of the
fish disease furunculosis, have been isolated for decades but very few of them have been …

Metagenomics has enabled sequencing of viral communities from a myriad of different
environments. Viral metagenomic studies routinely uncover sequences with no recognizable …

Alphaherpesviruses, as large double-stranded DNA viruses, were long considered to be
genetically stable and to exist in a homogeneous state. Recently, the proliferation of high …