Publisher Summary This chapter discusses gramicidin with respect to its structure and why it
is believed to be a channel. The gramicidins, of which there are several, are linear 15-amino …

Transport of ions across biological membranes is a ubiquitous mechanism for physiological
processes as disparate as nerve im-pulse propagation, 1 muscle action, 2 visual …

Simultaneous occupancy of the two binding sites in gramicidin A by monovalent cations is a
well known property of this channel, but the energetic feasibility of this process in molecular …

The outer membranes of plant cells contain channels which are highly selective for K+. In
the giant-celled green alga Chara corallina, K+ currents in the plasmalemma were …

The exchange diffusions of tracer cations (22 Na+, 86 Rb+) are studied on gramicidin-A-
traeted red blood cell (RBC) membranes. A time-dependent decrease in cation permeability …

Polyprenols have been found in many bacterial and plant membrane fractions. Long-chain
polyprenols with 12–100 isoprene residues have been isolated from the green leaves of …

Channel inactivation, a time-dependent decrease of the high-cationic permeability induced
by gramicidin A, has been found both in cholesterol containing red blood cell membranes …

Nonlinear least squares fitting was used to assign rate constants for the three-barrier, two-
site, double-occupancy, single-filing kinetic model for previously reported current–voltage …

Gramicidin A pores are permeable to water and small monovalent cations. For K, Rb, and Cs
there is good evidence from conductances and permeability ratios that a second ion can …

The transfer of ions across lipid bilayer membranes requires trace amounts of either" carrier"
or" pore-forming" molecules which facilitate the passage of ions through the hydrophobic …