Unlocking the Therapeutic Potential of Medicinal Plants for Alzheimer's Disease: Preclinical to Clinical Trial Insights

K Nagori, KT Nakhate, K Yadav, Ajazuddin… - Future …, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive, multifactorial, and unremitting neurodegenerative
disease characterized by memory loss, personality changes, and cognitive impairment. It …

Biomacromolecule-based nanocarrier strategies to deliver plant-derived bioactive components for cancer treatment: A recent review

B Gorain, V Karmakar, B Sarkar, M Dwivedi… - International journal of …, 2023 - Elsevier
The quest for safe chemotherapy has attracted researchers to explore anticancer potential of
herbal medicines. Owing to upsurging evidence of herbal drug's beneficial effects, hopes …

[HTML][HTML] Pinostrobin induces acute leukemia cell apoptosis via the regulation of miR-410-5p and SFRP5

C Norkaew, S Roytrakul, S Charoenlappanit… - Life Sciences, 2023 - Elsevier
Aims This study attempted to explore the mechanisms involved in pinostrobin (PN)-mediated
acute leukemia cell apoptosis regulated by miR-410-5p. Material and methods NB4 and …

Porous hydroxyapatite carrier enables localized and sustained delivery of honokiol for glioma treatment

FH Lin, YC Hsu, KC Chang, YJ Shyong - European Journal of …, 2023 - Elsevier
The objective of this study is to develop hydroxyapatite (HAp) particles for targeted delivery
of honokiol to tumor sites after glioma surgical management. Honokiol is released from the …

[PDF][PDF] Anti-proliferation and induction of mitochondria-mediated apoptosis by Garcinia hanburyi resin in colorectal cancer cells

K Vichitsakul, K Laowichuwakonnukul… - Heliyon, 2023 - cell.com
Abstract Introduction Several parts of Garcinia hanburyi are used in traditional medicine for
many purposes. In this study, Garcinia hanburyi resin (GHR) was explored for possible anti …

Urtica dioica Leaf Infusion Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Cisplatin Treatment

G Nafeh, M Abi Akl, J Samarani, R Bahous, G Al Kari… - Pharmaceuticals, 2023 - mdpi.com
Urtica dioica (UD) has been widely used in traditional medicine due to its therapeutic
benefits, including its anticancer effects. Natural compounds have a promising potential …

In vitro antithrombotic, antitumor and antiangiogenic activities of green tea polyphenols and its main constituent epigallocatechin-3-gallate

JRD Luz, JA López, MP Ferreira, RM de Sousa… - Processes, 2022 - mdpi.com
The balance between embolic risk and bleeding represents a clinical challenge in cancer
patient treatment, encouraging studies on adjuvant oncologic treatments. Thereby, this study …

Synthesis, characterization, and toxicity assessments of Silymarin-loaded Ni-Fe Metal-organic frameworks: Evidence from in vitro and in vivo evaluations

F Rahimi, S Shahraki, MR Hajinezhad… - Journal of Drug Delivery …, 2024 - Elsevier
Multiple investigations indicated that Silymarin (Syl), a flavonolignan extracted from the
Silybum marianum plant, might possess anticancer properties. It is also advertised as a liver …

Exploring Synergistic Interactions between Natural Compounds and Conventional Chemotherapeutic Drugs in Preclinical Models of Lung Cancer

M Boța, L Vlaia, AR Jîjie, I Marcovici, F Crişan… - Pharmaceuticals, 2024 - mdpi.com
In the current work, the synergy between natural compounds and conventional
chemotherapeutic drugs is comprehensively reviewed in light of current preclinical research …

[PDF][PDF] Effects of barakol from Cassia siamea on neuroblastoma SH-SY5Y cell line: A potential combined therapy with doxorubicin

O Wongsawatkul, P Buachan, Y Jaisin… - Heliyon, 2024 - cell.com
Management of neuroblastoma is challenging because of poor response to drugs,
chemotherapy resistance, high relapse, and treatment failures. Doxorubicin is a potent …