Light response of retinal ON bipolar cells requires a specific splice variant of Gαo

A Dhingra, M Jiang, TL Wang, A Lyubarsky… - Journal of …, 2002 - Soc Neuroscience
Glutamate released onto retinal ON bipolar neurons binds to a metabotropic receptor to
activate a heterotrimeric G-protein (Go) that ultimately closes a nonspecific cation channel …

Relationships between β-and α2-adrenoceptors and G coupling proteins in the human brain: effects of age and suicide

M Sastre, J Guimón, JA Garcı́a-Sevilla - Brain research, 2001 - Elsevier
Interactions between brain α2-and β-adrenoceptors are of interest in physiological (aging)
and pathological (major depression) processes involving both receptors. In this study, total β …

Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor‐differentiated PC12 cells

X Li, RS Jope - Journal of neurochemistry, 1995 - Wiley Online Library
This investigation examined if lithium, the primary therapeutic treatment for bipolar affective
disorder, modulated the levels of selected signal transduction proteins in PC12 cells. Nerve …

Mice lackingSnrpn expression show normal regulation of neuronal alternative splicing events

JD Huntriss, JA Barr, DA Horn, DG Williams… - Molecular Biology …, 1994 - Springer
The SmN protein is closely related to the constitutively expressed RNA splicing protein SmB
but is expressed only in brain and heart tissue. Mice which lack expression of SmN die …

Effect of thyroid deficiency on Go α-subunit isoforms in developing rat cerebral cortex

PP Li, S Andreopoulos, CC Wong, GG Vecil… - Neurochemical …, 1995 - Springer
Postnatal development of Gα o isoforms in rat cerebral cortex was studied by SDS-PAGE
and immunoblotting. When rat cerebral cortical membranes were resolved on separating …

Signal processing by the mammalian retina near absolute visual threshold

H Okawa - 2009 - search.proquest.com
When few photons are available, such as on a moonless night, our vision is limited by the
probability of photon absorption in rod photoreceptors, and the reliable transmission of light …

[图书][B] Clinical and functional investigations of the tissue specific SmN protein

JDA Huntriss - 1995 - search.proquest.com
The SmN protein is highly homologous to the constitutively expressed small nuclear
ribonucleoprotein particle (snRNP)-associated protein SmB but is expressed in brain and …