Multiple myeloma: diagnosis and treatment

SV Rajkumar, S Kumar - Mayo Clinic Proceedings, 2016 - Elsevier
The diagnosis and treatment of multiple myeloma has changed dramatically in the past
decade. The disease definition has been updated to include highly specific biomarkers in …

Prophylaxis for Pneumocystis pneumonia (PCP) in non‐HIV immunocompromised patients

A Stern, H Green, M Paul, L Vidal… - Cochrane database of …, 2014 - cochranelibrary.com
Background Pneumocystis pneumonia (PCP) is a disease affecting immunocompromised
patients. PCP among these patients is associated with significant morbidity and mortality …

[HTML][HTML] Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patients

C Blimark, E Holmberg, UH Mellqvist, O Landgren… - …, 2015 - ncbi.nlm.nih.gov
Infections are a major cause of morbidity and mortality in patients with multiple myeloma. To
estimate the risk of bacterial and viral infections in multiple myeloma patients, we used …

[HTML][HTML] European Myeloma Network guidelines for the management of multiple myeloma-related complications

E Terpos, M Kleber, M Engelhardt, S Zweegman… - …, 2015 - ncbi.nlm.nih.gov
Abstract The European Myeloma Network provides recommendations for the management
of the most common complications of multiple myeloma. Whole body low-dose computed …

International Myeloma Working Group recommendations for global myeloma care

H Ludwig, JS Miguel, MA Dimopoulos, A Palumbo… - Leukemia, 2014 - nature.com
Recent developments have led to remarkable improvements in the assessment and
treatment of patients with multiple myeloma (MM). New technologies have become available …

[HTML][HTML] Secondary immunodeficiency in hematological malignancies: focus on multiple myeloma and chronic lymphocytic leukemia

A Allegra, A Tonacci, C Musolino, G Pioggia… - Frontiers in …, 2021 - frontiersin.org
Secondary immunodeficiency is reported in most patients with hematological malignancies
such as chronic lymphocytic leukemia and multiple myeloma. The aim of our review was to …

Levofloxacin prophylaxis in patients with newly diagnosed myeloma (TEAMM): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial

MT Drayson, S Bowcock, T Planche, G Iqbal… - The Lancet …, 2019 - thelancet.com
Background Myeloma causes profound immunodeficiency and recurrent, serious infections.
Around 5500 new cases of myeloma are diagnosed per year in the UK, and a quarter of …

Secondary immunodeficiency in lymphoproliferative malignancies

V Friman, O Winqvist, C Blimark… - Hematological …, 2016 - Wiley Online Library
Secondary immunodeficiencies occur as a consequence of various diseases, including
hematological malignancies, and the use of pharmacological therapies, such as …

Prevention of infections including vaccination strategies in multiple myeloma

H Ludwig, S Kumar - American journal of hematology, 2023 - Wiley Online Library
Infections are a major cause of morbidity and mortality in multiple myeloma. The increased
risk for bacterial and viral infections results mainly from the disease‐inherent and treatment …

Management of infectious complications in multiple myeloma patients: expert panel consensus-based recommendations

C Girmenia, M Cavo, M Offidani, F Scaglione, A Corso… - Blood Reviews, 2019 - Elsevier
The introduction of new therapeutic agents in multiple myeloma (MM), including proteasome
inhibitors, immunoregulatory drugs and monoclonal antibodies, has improved the outcomes …