The impact of oxidative stress in male infertility

A Mannucci, FR Argento, E Fini, ME Coccia… - Frontiers in Molecular …, 2022 - frontiersin.org
At present infertility is affecting about 15% of couples and male factor is responsible for
almost 50% of infertility cases. Oxidative stress, due to enhanced Reactive Oxygen Species …

Mitochondria: their role in spermatozoa and in male infertility

M Boguenet, PE Bouet, A Spiers… - Human …, 2021 - academic.oup.com
BACKGROUND The best-known role of spermatozoa is to fertilize the oocyte and to transmit
the paternal genome to offspring. These highly specialized cells have a unique structure …

Multifunctional 4D‐Printed Sperm‐Hybrid Microcarriers for Assisted Reproduction

F Rajabasadi, S Moreno, K Fichna, A Aziz… - Advanced …, 2022 - Wiley Online Library
Remotely controllable microrobots are appealing for various biomedical in vivo applications.
In particular, in recent years, our group has focused on developing sperm‐microcarriers to …

[HTML][HTML] Pinostrobin alleviates testicular and spermatological damage induced by polystyrene microplastics in adult albino rats

MU Ijaz, S Najam, A Hamza, R Azmat, A Ashraf… - Biomedicine & …, 2023 - Elsevier
Abstract Background Polystyrene microplastics (PS-MPs) have become major
environmental pollutants that adversely effects multiple organs specifically testicles …

Sperm oxidative stress during in vitro manipulation and its effects on sperm function and embryo development

R Gualtieri, G Kalthur, V Barbato, S Longobardi… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) generated at low levels during mitochondrial respiration
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …

Mitochondria quality control and male fertility

J Costa, PC Braga, I Rebelo, PF Oliveira, MG Alves - Biology, 2023 - mdpi.com
Simple Summary Mitochondria play a crucial role in numerous cellular processes, including
energy production, apoptosis, and calcium homeostasis. In the male reproductive system …

Causes and consequences of sperm mitochondrial dysfunction

D Durairajanayagam, D Singh, A Agarwal… - Andrologia, 2021 - Wiley Online Library
Mitochondria have multiple functions, including synthesis of adenine triphosphate,
production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis …

Oxidative stress-induced apoptosis and autophagy: Balancing the contrary forces in spermatogenesis

P Sharma, N Kaushal, LR Saleth, S Ghavami… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Spermatogenesis is a complex process in the testis and is a cornerstone of male infertility.
The abundance of unsaturated fatty acid and high cell division rate make male germs cells …

Structure and function of ion channels regulating sperm motility—an overview

K Nowicka-Bauer, M Szymczak-Cendlak - International journal of …, 2021 - mdpi.com
Sperm motility is linked to the activation of signaling pathways that trigger movement. These
pathways are mainly dependent on Ca2+, which acts as a secondary messenger. The …

Oxidative stress and male infertility: evidence from a research perspective

B Ayad, TS Omolaoye, N Louw… - … in reproductive health, 2022 - frontiersin.org
Male fertility potential can be influenced by a variety of conditions that frequently coincide.
Spermatozoa are particularly susceptible to oxidative damage due to their limited …