Bone marrow mesenchymal stromal cells: identification, classification, and differentiation
Q Gao, L Wang, S Wang, B Huang, Y Jing… - Frontiers in cell and …, 2022 - frontiersin.org
Bone marrow mesenchymal stromal cells (BMSCs), identified as pericytes comprising the
hematopoietic niche, are a group of heterogeneous cells composed of multipotent stem …
hematopoietic niche, are a group of heterogeneous cells composed of multipotent stem …
Living on the edge of the CNS: meninges cell diversity in health and disease
The meninges are the fibrous covering of the central nervous system (CNS) which contain
vastly heterogeneous cell types within its three layers (dura, arachnoid, and pia). The dural …
vastly heterogeneous cell types within its three layers (dura, arachnoid, and pia). The dural …
Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis
Cranial neural crest cells are an evolutionary innovation of vertebrates for craniofacial
development and function, yet the mechanisms that govern the cell fate decisions of …
development and function, yet the mechanisms that govern the cell fate decisions of …
A multi-stem cell basis for craniosynostosis and calvarial mineralization
S Bok, AR Yallowitz, J Sun, J McCormick, M Cung… - Nature, 2023 - nature.com
Craniosynostosis is a group of disorders of premature calvarial suture fusion. The identity of
the calvarial stem cells (CSCs) that produce fusion-driving osteoblasts in craniosynostosis …
the calvarial stem cells (CSCs) that produce fusion-driving osteoblasts in craniosynostosis …
Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response
AZ Wang, JA Bowman-Kirigin, R Desai, LI Kang… - Genome medicine, 2022 - Springer
Background Recent investigations of the meninges have highlighted the importance of the
dura layer in central nervous system immune surveillance beyond a purely structural role …
dura layer in central nervous system immune surveillance beyond a purely structural role …
The clinical manifestations, molecular mechanisms and treatment of craniosynostosis
E Stanton, M Urata, JF Chen… - Disease Models & …, 2022 - journals.biologists.com
Craniosynostosis is a major congenital craniofacial disorder characterized by the premature
fusion of cranial suture (s). Patients with severe craniosynostosis often have impairments in …
fusion of cranial suture (s). Patients with severe craniosynostosis often have impairments in …
Single-cell analysis of lizard blastema fibroblasts reveals phagocyte-dependent activation of Hedgehog-responsive chondrogenesis
AC Vonk, X Zhao, Z Pan, ML Hudnall… - Nature …, 2023 - nature.com
Lizards cannot naturally regenerate limbs but are the closest known relatives of mammals
capable of epimorphic tail regrowth. However, the mechanisms regulating lizard blastema …
capable of epimorphic tail regrowth. However, the mechanisms regulating lizard blastema …
Expansion of the sagittal suture induces proliferation of skeletal stem cells and sustains endogenous calvarial bone regeneration
ZA Aldawood, L Mancinelli, X Geng… - Proceedings of the …, 2023 - National Acad Sciences
In newborn humans, and up to approximately 2 y of age, calvarial bone defects can naturally
regenerate. This remarkable regeneration potential is also found in newborn mice and is …
regenerate. This remarkable regeneration potential is also found in newborn mice and is …
A single‐cell transcriptomic atlas characterizes age‐related changes of murine cranial stem cell niches
The craniofacial bones provide structural support for the skull and accommodate the
vulnerable brain tissue with a protective cavity. The bone tissue undergoes constant …
vulnerable brain tissue with a protective cavity. The bone tissue undergoes constant …
Dynamic enhancer landscapes in human craniofacial development
The genetic basis of human facial variation and craniofacial birth defects remains poorly
understood. Distant-acting transcriptional enhancers control the fine-tuned spatiotemporal …
understood. Distant-acting transcriptional enhancers control the fine-tuned spatiotemporal …