The extracellular forms of the IL‐1 cytokines are active through binding to specific receptors
on the surface of target cells. IL‐1 ligands bind to the extracellular portion of their ligand …

Non-alcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease
in industrialized countries. NAFLD progresses through the inflammatory phase of non …

Indirubin plays an important role in the treatment of many chronic diseases and exhibits
strong anti-inflammatory activity. However, the molecular mode of action during mastitis …

Periodontitis, or gum disease, affects millions of people each year. Although it is associated
with a defined microbial composition found on the surface of the tooth and tooth root, the …

The aim of this study was to establish a link between periodontal disease and Alzheimer's
disease (AD) with a view to identifying the major periodontal disease bacteria (Treponema …

Background and aims Gut microbiota plays a major role in metabolic disorders. Berberine is
used to treat obesity, diabetes and atherosclerosis. The mechanism underlying the role of …

Important metabolic functions have been identified for the gut microbiota in health and
disease. Several lines of evidence suggest a role for the gut microbiota in both the etiology …

Compelling evidence supports the concepts that gut microbiota actively promotes weight
gain and fat accumulation and sustains, indirectly, a condition of low-grade inflammation …

In macrophages detection of gram-negative bacteria particularly involves binding of the
outer-wall component lipopolysaccharide (LPS) to its cognate receptor complex, comprising …

Uterine health is often compromised in cattle because postpartum contamination of the
uterine lumen by bacteria is ubiquitous, and pathogenic bacteria frequently persist causing …