[HTML][HTML] A concise profile of gallic acid—From its natural sources through biological properties and chemical methods of determination

D Wianowska, M Olszowy-Tomczyk - Molecules, 2023 - mdpi.com
Nature is a valuable source of anti-oxidants that have a health-promoting effect by inhibiting
various undesirable changes leading to cell degradation and, consequently, potential …

Gallic acid and gallates in human health and disease: do mitochondria hold the key to success?

RY Kosuru, A Roy, SK Das… - Molecular nutrition & food …, 2018 - Wiley Online Library
Gallic acid and gallate esters are widely used as dietary supplements or additives with
clinical significances. Over the last few decades, a large number of publications have been …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress are involved in the mechanism of methotrexate-induced renal injury and electrolytes imbalance

R Heidari, A Ahmadi, H Mohammadi… - Biomedicine & …, 2018 - Elsevier
Methotrexate is a folate analog used against a wide range of diseases including
malignancies and autoimmune disorders. On the other hand, clinical use of the MTX is …

Evaluating the influence of Aloe barbadensis extracts on edema induced changes in C-reactive protein and interleukin-6 in albino rats through in vivo and in silico …

B Rauf, S Alyasi, N Zahra, S Ahmad… - Acta Biochimica …, 2023 - abp.ptbioch.edu.pl
The current study investigated the in-vivo and in-silico anti-inflammatory effect of Aloe
barbadensis in edema induced rat and its blood biomarkers. 60 albino rats (160-200 g) were …

Antioxidant and anti-apoptotic potency of allicin and lycopene against methotrexate-induced cardiac injury in rats

M Aboubakr, A Farag, A Elfadadny, M Alkafafy… - … Science and Pollution …, 2023 - Springer
This study aimed to explore whether allicin (ALC) and lycopene (LP) could offer protection
against the harmful effects of methotrexate (MTX), a type of chemotherapy drug known for its …

Gallic acid protects against Aflatoxin B1‐induced oxidative and inflammatory stress damage in rats kidneys and liver

S Owumi, ES Najophe, EO Farombi… - Journal of food …, 2020 - Wiley Online Library
The adverse effect of Aflatoxin B1 (AFB1) exposure in both humans and rodents has been
widely reported. The beneficial health effects of gallic acid (GA) against AFB1‐induced …

Gallic acid and/or cerium oxide nanoparticles synthesized by gamma-irradiation protect cisplatin-induced nephrotoxicity via modulating oxidative stress, inflammation …

M Saif-Elnasr, S El-Ghlban, AI Bayomi… - Archives of Biochemistry …, 2023 - Elsevier
Cisplatin is one of the most significant anticancer. However, its use is associated with
numerous toxicities especially nephrotoxicity. The main aim of this work was to examine the …

Apigenin alleviates methotrexate-induced liver and kidney injury in mice

F Sahindokuyucu-Kocasari, Y Akyol… - Human & …, 2021 - journals.sagepub.com
Methotrexate (MTX) is a drug used in the treatment of various types of cancer and
inflammatory diseases, but its clinical use has been restricted due to its toxicity. Apigenin …

[HTML][HTML] Protective effect of gallic acid and gallic acid-loaded Eudragit-RS 100 nanoparticles on cisplatin-induced mitochondrial dysfunction and inflammation in rat …

MA Dehghani, NS Maram, E Moghimipour… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Cisplatin is used as a chemotherapy drug in the treatment of various types of cancer.
Mitochondrial dysfunction, oxidative stress and inflammation have been identified as major …

[HTML][HTML] Tea and its components reduce the production of uric acid by inhibiting xanthine oxidase

D Wu, R Chen, W Zhang, X Lai, L Sun, Q Li… - Food & Nutrition …, 2022 - ncbi.nlm.nih.gov
Background The health benefits of tea are as diverse including the reduction of uric acid
levels. Xanthine oxidase is the most directly mediated enzyme in the production of uric acid …