The present study was designed to evaluate the possible protective effects of melatonin
(MEL) and/or l-carnitine (L-CAR) against methotrexate (MTX)-induced toxicity in isolated rat …

In vitro and in vivo antioxidant activities of the Vietnam-grown Ophiocordyceps sobolifera
were investigated for the first time. The contents of phenolic and flavonoid compounds found …

Isotopic analyses and chromatographic analysis (phenolic compounds and biogenic
amines), can be applied to investigate the functional and nutritional quality in different grape …

Oxidative stress is the underlying cause of various chronic diseases and can contribute to its
progression. Plant‐based therapeutics are effective in the prevention of various chronic …

Aflatoxins are harmful natural contaminants found in foods and are known to be hepatotoxic.
However, recent studies have linked chronic consumption of aflatoxins to nephrotoxicity in …

Background Methotrexate (MTX) is one of chemotherapeutic drugs that induce several side
effects. The present study aimed to investigate the ameliorative effect of human placental …

We investigated the possible ameliorative effects of nobiletin (NBL) against methotrexate
(MTX)-induced hepatorenal toxicity in rats. Twenty-eight Wistar albino rats were randomly …

Objective: This study was purposed to investigate the possible protective effects of rutin on
kidney tissue in a methotrexate-induced nephrotoxicity rat model. Methods: Rats were …

Abstract Tacrolimus (FK506), a calcineurin inhibitor, is an effective immunosuppressive
agent mainly used to lower the risk of organ rejection after allogeneic organ transplant …

Background Methotrexate (MTX) is a folic acid antagonist, commonly administered for the
treatment of a variety of cancers. However, methotrexate toxicity including bone marrow …