Psychedelic compounds, including psilocybin, LSD, DMT, and 5-MeO-DMT all of which are
serotonin (5-HT) 2A receptor agonists are being investigated as potential treatments. This …

In clinical practice, it is frequently observed that cardiac and psychological disorders
frequently co-occur, leading to the emergence of a field known as cardiovascular disease …

Drug-induced cardiotoxicity (DICT) is a major concern in drug development, accounting for
10–14% of postmarket withdrawals. In this study, we explored the capabilities of chemical …

Acute myocardial infarction (AMI) is one of the leading causes of death worldwide and
treatment costs pose a major burden on the global health care system. Despite the variety of …

Within drug development, high off-target promiscuity as well as potent cytotoxicity, are
associated with a high attrition rate. We investigated the safety profile of novel plasmepsin X …

Lysergic acid diethylamide (LSD) is an artificial hallucinogenic drug. Thus, we hypothesized
that LSD might act 5-HT4 serotonin receptors and/or H2 histamine receptors. We studied …

Serotonin, or 5-hydroxytryptamine (5-HT), is a neurotransmitter with an integral physiological
role in the human body; it is involved in regulating various activities (eg, behavior, mood …

The current research aims to study the therapeutic efficacy of alpha-lipoic acid (α-LA) and
caffeine-loaded chitosan nanoparticles (Caf-CNs) against cardiovascular complications …

Psychedelics are powerful psychoactive substances that alter perception and mood
processes. Their effectiveness in the treatment of psychiatric diseases was known before …

Glucagon exerts effects on the mammalian heart. These effects include alterations in the
force of contraction, beating rate, and changes in the cardiac conduction system axis. The …