[HTML][HTML] Recruitment and retention interventions in surgical and wound care trials: A systematic review

C Arundel, A Mott - PLoS One, 2023 - journals.plos.org
Background Recruitment and retention to surgical trials has previously been reported to be
problematic, resulting in research waste. Surgery often results in wounds, meaning these …

Eligibility criteria in NIH-funded clinical trials: Can adults with intellectual disability get in?

KE McDonald, AE Schwartz, M Sabatello - Disability and Health Journal, 2022 - Elsevier
Background Although scientific breakthroughs can promote health equity, there is concern
that adults with intellectual disability, a health disparities population, may be excluded from …

Effectiveness and safety of menopause treatments: pitfalls of available evidence and future research need

BH Al Wattar, E Rogozińska, C Vale, D Fisher… - …, 2024 - Taylor & Francis
Abstract By 2050 more than 1.6 billion women worldwide will be of post-reproductive age,
with> 75% reporting severe menopausal symptoms. The last few years saw a gradual uplift …

Methods of Recruitment for Surgical and Perioperative Randomized Controlled Trials: A Rapid Review

MM Ninomiya, J Hiemstra, E Nicholson… - World Journal of Surgery, 2023 - Springer
Due to the complex nature of surgical randomized controlled trials (RCTs), reaching target
recruitment can be challenging. The primary objective was to report on characteristics of …

[HTML][HTML] Understanding the perspectives of recruiters is key to improving randomised controlled trial enrolment: a qualitative evidence synthesis

N Farrar, D Elliott, C Houghton, M Jepson, N Mills… - Trials, 2022 - Springer
Background Recruiting patients to randomised controlled trials (RCTs) is often reported to
be challenging, and the evidence base for effective interventions that could be used by staff …

[HTML][HTML] Exploring implementation outcomes in the clinical trial context: a qualitative study of physician trial stakeholders

KD Stensland, AE Sales, VK Vedapudi… - Trials, 2023 - Springer
Introduction Cancer clinical trials can be considered evidence-based interventions with
substantial benefits, but suffer from poor implementation leading to low enrollment and …

[HTML][HTML] The integration of rapid qualitative research in clinical trials: reflections from the ward-based goal-directed fluid therapy (GDFT) in acute pancreatitis feasibility …

C Vindrola-Padros, F Froghi, V Gopalan, S Maruthan… - Trials, 2023 - Springer
Background There has been an increase in the integration of qualitative studies in
randomised controlled trials. The purpose of this article is to reflect on our experience of …

[HTML][HTML] Approaches and experiences implementing remote, electronic consent at the Leeds Clinical Trials Research Unit

WJ Cragg, C Taylor, L Moreau, H Collier, R Gilberts… - Trials, 2024 - Springer
Background Use of electronic methods to support informed consent ('eConsent') is
increasingly popular in clinical research. This commentary reports the approach taken to …

MultiSCRIPT-Cycle 1-A Pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized …

P Janiaud, C Zecca, A Salmen, P Benkert… - medRxiv, 2024 - medrxiv.org
Background: Treatment decisions for persons with relapsing-remitting multiple sclerosis
(RRMS) rely on clinical and radiological disease activity, the benefit-harm profile of drug …

The Hand and Wrist: AntImicrobials and Infection (HAWAII) trial

JCR Wormald, J Rodrigues, R Bheekharry… - British Journal of …, 2023 - academic.oup.com
Background Hand trauma, comprising injuries to both the hand and wrist, affects over five
million people per year in the NHS, resulting in 250 000 operations each year. Surgical site …