Amyloid fibrils have excellent structural characteristics, such as a high aspect ratio, excellent
stiffness, and a wide availability of functional groups on the surface. More studies are now …

Neurodegenerative diseases (NDs) are often age-related disorders that can cause dementia
in people, usually over 65 years old, are still lacking effective therapies. Some NDs have …

Memory impairment is a result of multiple factors including amyloid-beta (Aβ) accumulation.
Several receptors are mediated for Aβ transport and signaling. Moreover, blood lipids are …

Amyloid aggregation of protein is linked to many neurodegenerative diseases. Identification
of small molecules capable of targeting amyloidogenic proteins has gained significant …

Proteins are major drug targets, and drug–target interaction identification and analysis are
important factors for drug discovery. Atomic force microscopy (AFM) is a powerful tool …

Our study aimed to investigate the effects of ultrasound on the fibrillation kinetics of HEWL
(hen egg white lysozyme) and its physicochemical properties. Ultrasound, a mechanical …

Protein acetylation is a significant post-translational modification, and hyperacetylation
results in amyloid aggregation, which is closely related to neurodegenerative diseases …

Neurodegenerative diseases are a group of debilitating maladies involving protein
aggregation. To this day, all advances in neurodegenerative disease therapeutics have …

Carbon nanodots (CNDs) were facilely synthesized through a pyrolysis procedure with
histamine, an amino acid rich in element carbon and nitrogen, being the precursor. Taking …

The inhibition of human islet amyloid polypeptide (hIAPP) deposition to block its toxicity is an
important strategy for the prevention and treatment of type II diabetes mellitus (T2DM) …