Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …

Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with a
considerable socioeconomic burden. Heterogeneity of pathoanatomical subtypes and …

Inflammatory reactions could be both beneficial and detrimental to the brain, depending on
strengths of their activation in various stages of neurodegeneration. Mild activation of …

Triggering receptor expressed on myeloid cells 2 (TREM2) is a single-pass transmembrane
immune receptor that is mainly expressed on microglia in the brain and macrophages in the …

Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Traumatic brain injury (TBI) represents a major cause of death and disability in developed
countries. Brain injuries are highly heterogeneous and can also trigger other neurological …

Traumatic brain injury (TBI) refers to any insult to the brain resulting in primary (direct) and
secondary (indirect) damage to the brain parenchyma. Secondary damage is often linked to …

Misfolded proteins in the central nervous system can induce oxidative damage, which can
contribute to neurodegenerative diseases in the mitochondria. Neurodegenerative patients …

Traumatic brain injury (TBI) is a serious public health problem accounting for 1.4 million
emergency room visits by US citizens each year. Although TBI has been traditionally …

Neuroinflammation is a physiological protective response in the context of infection and
injury. However, neuroinflammation, especially if chronic, may also drive …