Paradigms of acute kidney injury in the intensive care setting
Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies,
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …
Sepsis-induced acute kidney injury revisited: pathophysiology, prevention and future therapies
An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the
important role of maladaptive responses to the septic insult. Preventive and therapeutic …
important role of maladaptive responses to the septic insult. Preventive and therapeutic …
Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American …
Methods These are the consensus statements and guideline of ASHP, IDSA, the Pediatric
Infectious Diseases Society (PIDS), and SIDP. Guideline panel composition consisted of …
Infectious Diseases Society (PIDS), and SIDP. Guideline panel composition consisted of …
Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study
Purpose Current reports on acute kidney injury (AKI) in the intensive care unit (ICU) show
wide variation in occurrence rate and are limited by study biases such as use of incomplete …
wide variation in occurrence rate and are limited by study biases such as use of incomplete …
Inhibition of ALKBH5 attenuates I/R-induced renal injury in male mice by promoting Ccl28 m6A modification and increasing Treg recruitment
J Chen, C Xu, K Yang, R Gao, Y Cao, L Liang… - Nature …, 2023 - nature.com
Ischemia reperfusion injury (IRI) is a common cause of acute kidney injury (AKI). The role of
N6-methyladenosine (m6A) modification in AKI remains unclear. Here, we characterize the …
N6-methyladenosine (m6A) modification in AKI remains unclear. Here, we characterize the …
Gut bacteria products prevent AKI induced by ischemia-reperfusion
V Andrade-Oliveira, MT Amano… - Journal of the …, 2015 - journals.lww.com
Short-chain fatty acids (SCFAs) are fermentation end products produced by the intestinal
microbiota and have anti-inflammatory and histone deacetylase–inhibiting properties …
microbiota and have anti-inflammatory and histone deacetylase–inhibiting properties …
Inflammation in kidney repair: Mechanism and therapeutic potential
Y Fu, Y Xiang, H Li, A Chen, Z Dong - Pharmacology & therapeutics, 2022 - Elsevier
The kidney has a remarkable ability of repair after acute kidney injury (AKI). However, when
injury is severe or persistent, the repair is incomplete or maladaptive and may lead to …
injury is severe or persistent, the repair is incomplete or maladaptive and may lead to …
[HTML][HTML] Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus …
Over the last decade there has been considerable progress in the discovery and
development of biomarkers of kidney disease, and several have now been evaluated in …
development of biomarkers of kidney disease, and several have now been evaluated in …
Targeting acute kidney injury in COVID-19
JA Kellum, JWO van Till… - Nephrology Dialysis …, 2020 - academic.oup.com
Abstract As of 15 August 2020, Coronavirus disease 2019 (COVID-19) has been reported
in> 21 million people world-wide and is responsible for more than 750,000 deaths. The …
in> 21 million people world-wide and is responsible for more than 750,000 deaths. The …
A basic science view of acute kidney injury biomarkers
JR Charlton, D Portilla, MD Okusa - Nephrology Dialysis …, 2014 - academic.oup.com
Over the last decade, significant progress has been made in the identification and validation
of novel biomarkers as well as refinements in the use of serum creatinine as a marker of …
of novel biomarkers as well as refinements in the use of serum creatinine as a marker of …