Although the pathogenesis of neurodegenerative diseases is still widely unclear, various
mechanisms have been proposed and several pieces of evidence are supportive for an …

Neurodegenerative diseases (NDs) are a class of heterogeneous diseases that includes
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral …

Alzheimer's disease (AD) is the most frequent cause of age-related neurodegeneration and
cognitive impairment, and there are currently no broadly effective therapies. The underlying …

Neuronal mitochondrial dysfunction caused by excessive reactive oxygen species (ROS) is
an early event of sporadic Alzheimer's disease (AD), and considered to be a key pathologic …

Neurodegenerative diseases represent some of the most devastating neurological
disorders, characterized by progressive loss of the structure and function of neurons. Current …

Apart from ATP generation, mitochondria are involved in a wide range of functions, making
them one of the most prominent organelles of the human cell. Mitochondrial dysfunction is …

In neurodegenerative diseases, neurodegeneration has been related to several
mitochondrial dynamics imbalances such as excessive fragmentation of mitochondria …

Biomimetic nanotechnology represents a promising approach for the delivery of therapeutic
agents for the treatment of complex diseases. Recently, neuronal mitochondria have been …

Reactive oxygen species (ROS)-induced neuronal mitochondrial dysfunction is a key
pathologic factor in sporadic Alzheimer's disease (AD). Neuronal mitochondria have been …

Neurodegenerative disorders (NDDs) are characterized by progressive loss of selectively
vulnerable neuronal populations and myelin sheath, leading to behavioral and cognitive …